Sleep graphoelements dynamics and its impact on neurophysiology of patients with obstructive sleep apnea through electroencephalography signals

• Grant number: 12/22413-2
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: March 01, 2013
• End date: February 29, 2016
• Field of knowledge: Physical Sciences and Mathematics - Physics - Condensed Matter Physics
• Principal Investigator: Ney Lemke
• Grantee: Rafael Toledo Fernandes de Souza
• Host Institution: Instituto de Biociências (IBB). Universidade Estadual Paulista (UNESP). Campus de Botucatu. Botucatu , SP, Brazil

Abstract

The discovery of the electroencephalogram (EEG) allowed the study of brain electrical signals. The EEG is widely used in the sleep cycles study including related disorders such as Obstructive Sleep Apnea (OSA). This condition affects about 4% of men and 2% of women workforce. In this project is proposed the analysis of sleep graphoelements and correlate these graphoelements with neurophysiological functions and events. EEG examinations carried out in adult diagnosed with OSA will be used in the project. The detection of sleep spindles and K complexes will be carried out by computational methods based on time x frequency analysis. We will investigate correlations between topographic regions and the studied graphoelements, and investigate their impacts on human health.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

FERNANDES DE SOUZA, RAFAEL TOLEDO; LEWCZUK GERHARDT, GUENTHER JOHANNES; SCHOENWALD, SUZANA VEIGA; RYBARCZYK-FILHO, JOSE LUIZ; LEMKE, NEY. Synchronization and Propagation of Global Sleep Spindles. PLoS One, v. 11, n. 3, MAR 10 2016. (13/02018-4, 12/22413-2)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SOUZA, Rafael Toledo Fernandes de. Sleep graphoelements dynamics and its impact on the neurophysiology of patients with obstructive sleep apnea through electroencephalography signals. 2016. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Instituto de Biociências. Botucatu Botucatu.