Development and Long-term stability evaluation of sunscreen lip balm formulations

• Grant number: 12/13661-2
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: April 01, 2013
• End date: January 31, 2014
• Field of knowledge: Health Sciences - Pharmacy - Pharmaceutical Technology
• Principal Investigator: André Rolim Baby
• Grantee: Danielle Maeda Ideriha
• Host Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Endogenous protection mechanisms against damages promoted by solar radiation are insufficient, therefore it is important to use photoprotective formulations, both corporal and labial, in order to minimize the damages caused by this radiation. Lip balms are preparations that protect lips against adverse environmental factors and prevent them from drying. As an example, sunscreen lip balms, protect the lip mucous membrane from ultraviolet A and B radiation. They are composed of solar filters (active ingredients), additives, and greasy compounds, among others, which may influence the photoprotective efficacy of the preparation. This project's objectives are development of sunscreen lip balm formulations, physical and organoleptic characterization, in vitro efficacy evaluation by integrating sphere diffuse reflectance spectrophotometry, and evaluation the physical and functional stability of sunscreen lip balms by the long-term stability test. (AU)