| Grant number: | 13/04970-4 |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |
| Start date: | June 01, 2013 |
| End date: | June 30, 2015 |
| Field of knowledge: | Health Sciences - Physical Education |
| Principal Investigator: | Carlos Ugrinowitsch |
| Grantee: | Carla da Silva Batista |
| Host Institution: | Escola de Educação Física e Esporte (EEFE). Universidade de São Paulo (USP). São Paulo , SP, Brazil |
Abstract Decline in the neuromuscular function inherent to the aging process aggravate motor changes alterations produced by the Parkinson's disease (PD), such as bradykinesia, postural instability and rigidity. These motor symptoms interfere drastically when performing activities of daily living (i.e., functionality) of individuals with PD and cause frequent falls. Associated with these symptoms, a decrease in the ability to force production observed in these individuals also impairs the functionality and therefore increases the risk of falls and worsening the quality of life of this population. Additionally, such decrease in the ability to produce force may be a result of changes in some spinal inhibitory mechanisms due to abnormal efferent drive from the basal ganglia to the spinal cord of patients with PD. Thus, interventions that can slow or reverse this situation are extremely important for maintaining or improving the quality of life of this population. Previous studies have shown that strength training (ST) seems to be able to promote brain neuroplasticity and improve some functional deficits in individuals with PD by increasing muscle strength. However, the effects of this intervention on the ability to force production in spinal inhibitory mechanisms in motor symptoms, decreasing the risk of falling and quality of life of individuals with PD to date are unknown. Moreover, a training model that also increases muscle strength to enhance the functionality of individuals with PD, however, that requires a great demand proprioceptive and motor control during execution, may be more effective than the ST to improve all these variables described above. Accordingly, the functional training or ST under conditions of instability (STI) appears to be very promising since individuals with PD held power drills having a main support base (i.e., responsible for sustaining most of the body weight) of unstable conditions. However, analogously to ST the adjustments produced by STI in this population also are unknown. Thus, the objective of this study is to analyze and compare the effect of 12 weeks of ST and STI in the neuromuscular adaptations, functionality, motor symptoms, the risk of falling and quality of life of individuals in stage 2 and 3 of the PD and verify if individuals with PD who carry out the intervention of ST and STI will approach the situation of the healthy control after intervention both in functionality and in neuromuscular adaptations. | |
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