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Investigation of the use of alcohol and other drugs in patients with first psychotic episode

Grant number: 13/09110-3
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): July 01, 2013
Effective date (End): June 30, 2014
Field of knowledge:Health Sciences - Medicine - Psychiatry
Principal researcher:Quirino Cordeiro Júnior
Grantee:Maria Regina Coelho Junqueira
Home Institution: Faculdade de Ciências Médicas da Santa Casa de São Paulo (FCMSCSP). Fundação Arnaldo Vieira de Carvalho. São Paulo , SP, Brazil
Associated research grant:11/50740-5 - Prevention in schizophrenia and bipolar disorder from neuroscience to the community: a multiphase, multimodal and translational platform for research and intervention, AP.TEM


Schizophrenia is a psychiatric illness remarkable prevalence worldwide. In general, it affects young individuals, tracing a chronic and debilitating course. One of the main risk factors for the development of this pathology is the use of psychoactive substances (such as alcohol and illicit drugs). Recent research shows that the date of the first psychotic episode has been found high rates of use of toxic substances. This paper proposes to make a descriptive analysis of the pattern of use of alcohol and other drugs and to investigate its association with the severity of psychotic symptoms in patients with first episode psychosis, and to investigate the correlation between the use of alcohol and other drugs in sociodemographic variables such as gender, age of first psychotic episode and social support. To this end, this project aims to carry out a retrospective observational study - by conducting a descriptive analysis of the data collected in the initial assessment of patients included in the original research project (already explained in the presentation). The sample consists of 140 patients with first episode psychosis without prior use of antipsychotic medications. The expansion of knowledge about the associations of psychoactive substances and schizophrenia in its earliest stage can provide relevant information to early intervention and prevent unfavorable outcomes of schizophrenia. (AU)

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