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lipidomic analysis of some Amazonian fish

Grant number: 13/14707-9
Support Opportunities:Scholarships in Brazil - Doctorate
Start date: January 01, 2014
End date: March 31, 2017
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal Investigator:Ljubica Tasic
Grantee:Banny Silva Barbosa Correia
Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Associated scholarship(s):15/11359-5 - Target lipidomics of Amazonian fishes by liquid chromatography: mass spectrometry, BE.EP.DR

Abstract

The phospholipids presence in fish and their importance for human health is related, mainly, in the fact of some phospholipids contain omega 3 fatty acids in their structures. However, studies and characterization of these biomolecules in their intact form are still mencionated few times in the literature, above all about the Amazonian fish, besides the progresses in techniques for lipids determination, their analyses keep been challenging, because these complexity and specificity, which oppositely to the proteomic and genomic analysis, don't are sustained in information which can predict the number of individual molecules presented in one organism. This way, this project involves the investigation of phospholipids in nine Amazonian fishes species of different feed habits: tambaqui, sardinha, curimatã, pirarucu, jaraqui, surubim, mapará, pescada and tucunaré, in different seasonal time, through phospholipidomic analysis, as well the investigation of biosynthesis of these phospholipids, using chromatographic and spectroscopic techniques, as the mass spectrometry and the spectroscopy of nuclear magnetic resonance. Because there are no studies of these analysis' kind in Amazonian fishes, associated to the correlation of phospholipids containing omega 3 fatty acids with diseases treatment, because the fact to be precursors of eicosanoids, the hope is about the results which can contribute to beyond understanding better the biosyntetic route of Amazonian fishes' phospholipids, attribute importance to the structure in which this fatty acids are bonded.

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
BANNY S. B. CORREIA; GILBERTO G. D. ORTIN; NATALIA C. MOR; MAIARA S. SANTOS; RAQUEL S. TORRINHAS; ADALBERTO L. VAL; LJUBICA TASIC. NMR in Analysis of the Nutritional Value of Lipids from Muscles and Livers of Wild Amazonian Fishes with Different Eating Habits Over Seasonal Variation. Journal of the Brazilian Chemical Society, v. 31, n. 12, p. 2531-2543, . (13/14707-9, 14/11258-1)
MOR, NATALIA CRISTINA; CORREIA, BANNY S. B.; VAL, ADALBERTO LUIS; TASIC, LJUBICA. A Protocol for Fish Lipid Analysis Using Nuclear Magnetic Resonance Spectroscopy. Journal of the Brazilian Chemical Society, v. 31, n. 4, p. 662-672, . (13/14707-9, 14/11258-1)
BANNY S. B. CORREIA; JOÃO GUILHERME M. PONTES; RAQUEL SUSANA TORRINHAS; ADALBERTO LUIS VAL; CHRISTOPHER PAUL THOMAS; LJUBICA TASIC. Evaluation of the Amazon River Seasonal Influences on Glycerophospholipids in Wild Fish. Journal of the Brazilian Chemical Society, v. 35, n. 7, . (13/14707-9, 15/11359-5)
Academic Publications
(References retrieved automatically from State of São Paulo Research Institutions)
CORREIA, Banny Silva Barbosa. Lipidomic analysis of some amazonian fish. 2017. Doctoral Thesis - Universidade Estadual de Campinas (UNICAMP). Instituto de Química Campinas, SP.