| Grant number: | 13/14707-9 |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| Start date: | January 01, 2014 |
| End date: | March 31, 2017 |
| Field of knowledge: | Physical Sciences and Mathematics - Chemistry - Organic Chemistry |
| Principal Investigator: | Ljubica Tasic |
| Grantee: | Banny Silva Barbosa Correia |
| Host Institution: | Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil |
| Associated scholarship(s): | 15/11359-5 - Target Lipidomics of Amazonian Fishes by Liquid Chromatography-Mass Spectrometry, BE.EP.DR |
Abstract The phospholipids presence in fish and their importance for human health is related, mainly, in the fact of some phospholipids contain omega 3 fatty acids in their structures. However, studies and characterization of these biomolecules in their intact form are still mencionated few times in the literature, above all about the Amazonian fish, besides the progresses in techniques for lipids determination, their analyses keep been challenging, because these complexity and specificity, which oppositely to the proteomic and genomic analysis, don't are sustained in information which can predict the number of individual molecules presented in one organism. This way, this project involves the investigation of phospholipids in nine Amazonian fishes species of different feed habits: tambaqui, sardinha, curimatã, pirarucu, jaraqui, surubim, mapará, pescada and tucunaré, in different seasonal time, through phospholipidomic analysis, as well the investigation of biosynthesis of these phospholipids, using chromatographic and spectroscopic techniques, as the mass spectrometry and the spectroscopy of nuclear magnetic resonance. Because there are no studies of these analysis' kind in Amazonian fishes, associated to the correlation of phospholipids containing omega 3 fatty acids with diseases treatment, because the fact to be precursors of eicosanoids, the hope is about the results which can contribute to beyond understanding better the biosyntetic route of Amazonian fishes' phospholipids, attribute importance to the structure in which this fatty acids are bonded. | |
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