The effect of biofortified food consumption in the nutritional status of iron and vitamin A in pre-school children

• Grant number: 13/06979-9
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: July 01, 2014
• End date: June 30, 2016
• Field of knowledge: Health Sciences - Nutrition - Nutritional Analysis of Population
• Principal Investigator: Regina Mara Fisberg
• Grantee: Diva Aliete dos Santos Vieira
• Host Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

The association between elevated serum ferritin concentration and iron overload in insulin resistance has been discussed in scientific literature. Iron overload, by its pro-oxidant effect, contributes to the development of some systemic diseases. Recent studies suggest that oxidative stress caused by iron overload can cause injury in pancreatic ²-cells, reducing the production and secretion of insulin, contributing to the development of type 2 diabetes mellitus. Objective: To investigate the association between iron status and insulin resistance in adults and elderly in São Paulo. Method: Cross-sectional population-based survey ISA-Capital 2014 which will evaluated 629 adults and elderly living in the urban area of São Paulo, Brazil. Sociodemographic, lifestyle and family history of morbidity data were obtained by applying a structured questionnaire. Anthropometric measurements (weight, height and waist circumference) and blood pressure were collected and two 24-hour recall were applied for the estimation of usual dietary intake. The biomarkers of iron status (serum ferritin, transferrin, haemogram) will be assessed and insulin resistance will be estimated by the homeostasis model assessment of insulin resistance (HOMA-IR). The association between the iron status and insulin resistance is evaluated by structural equation model. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DOS SANTOS VIEIRA, DIVA ALIETE; CASTRO, MICHELLE ALESSANDRA; FISBERG, MAURO; FISBERG, REGINA MARA. Qualidade nutricional dos padrões alimentares de crianças: existem diferenças dentro e fora da escola?. Jornal de Pediatria, v. 93, n. 1, p. 47-57, JAN-FEB 2017. (13/06979-9)

FELIX DOS SANTOS, PAULA VICTORIA; SALES, CRISTIANE HERMES; SANTOS VIEIRA, DIVA ALIETE; FONTANELLI, MARIANE DE MELLO; MARCHIONI, DIRCE MARIA; FISBERG, REGINA MARA. Family income per capita, age, and smoking status are predictors of low fiber intake in residents of Sao Paulo, Brazil. Nutrition Research, v. 36, n. 5, p. 478-487, MAY 2016. (13/06979-9, 09/15831-0)

DOS SANTOS VIEIRA, DIVA ALIETE; SALES, CRISTIANE HERMES; GALVAO CESAR, CHESTER LUIZ; MARCHIONI, DIRCE MARIA; FISBERG, REGINA MARA. Influence of Haem, Non-Haem, and Total Iron Intake on Metabolic Syndrome and Its Components: A Population-Based Study. NUTRIENTS, v. 10, n. 3, MAR 2018. (13/06979-9, 12/22113-9)

DOS SANTOS VIEIRA, DIVA ALIETE; STELUTI, JOSIANE; VERLY-, JR., ELISEU; MARCHIONI, DIRCE MARIA; FISBERG, REGINA MARA. Brazilians' experiences with iron fortification: evidence of effectiveness for reducing inadequate iron intakes with fortified flour policy. PUBLIC HEALTH NUTRITION, v. 20, n. 2, p. 363-370, FEB 2017. (13/06979-9, 12/22113-9)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

VIEIRA, Diva Aliete dos Santos. Iron intake: dietary intake and its association with insulin resistance and metabolic syndrome in the era of mandatory fortification. 2016. Doctoral Thesis - Universidade de São Paulo (USP). Faculdade de Saúde Pública (FSP/CIR) São Paulo.