ANALYSIS OF NASAL AND SYSTEMIC INFLAMMATION REACTION IN SUGARCANE CUTTERS SUBJECT TO SEVERE PHYSICAL ACTIVITY AND EXPOSURE TO AIR POLLUTION

• Grant number: 14/08029-0
• Support Opportunities: Scholarships in Brazil - Master
• Start date: September 01, 2014
• End date: July 31, 2015
• Field of knowledge: Health Sciences - Physiotherapy and Occupational Therapy
• Principal Investigator: Dionei Ramos
• Grantee: Iara Buriola Trevisan
• Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil

Abstract

INTRODUCTION: The harvesting of sugarcane preceded by a burning exposes workers to high concentrations of pollutants added to the effects of strenuous physical labor can lead to increased release of inflammatory mediators both nasal and systemic. However, the consequences of exposure to pollution of biomass burning added to the peculiar conditions of employment in the nasal and systemic inflammation are still poorly studied in sugarcane cutters. OBJECTIVES: To assess the impacts of physical stress and air pollution plus the conditions of the working day on nasal and systemic inflammatory markers in sugarcane workers from the West of Sao Paulo State. METHODS: Sugarcane workers, male, aged between 18 and 45 years, smokers and nonsmokers will be evaluated. Evaluations shall be performed in the field planting sugar cane, where volunteers will first be interviewed by questionnaires. In addition to assessments of vital signs, carbon monoxide in exhaled air (exCO), collection of nasal lavage (NL) and blood collection, the following time: (a)the period between harvests; (b) harvest period. All reviews will be conducted in the morning between 7 and 9 A.M.. STATISTICAL ANALYSIS: The normal distribution of the data will be assessed by the Shapiro-Wilk test. For analysis between groups the unpaired t test or Mann- Whitney test and for intragroup analysis , will be used ANOVA for repeated measures followed by Tukey test or Friedman test followed by Dunn's test also depending on the normal distribution of data. Correlations will be evaluated using the Pearson or Spearman coefficients. The level of significance is p<0.05.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

TREVISAN, IARA BURIOLA; SANTOS, UBIRATAN DE PAULA; LEITE, MARCELI ROCHA; FERREIRA, ALINE DUARTE; DE ALENCAR SILVA, BRUNA SPOLADOR; COELHO FIGUEIRA FREIRE, ANA PAULA; SANTA BRIGIDA, GABRIEL FAUSTINO; CIPULO RAMOS, ERCY MARA; RAMOS, DIONEI. Colheita de cana-de-açúcar queimada está associada a sintomas de rinite e marcadores inflamatórios. Brazilian Journal of Otorhinolaryngology, v. 85, n. 3, p. 337-343, MAY-JUN 2019. (14/08029-0)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

TREVISAN, Iara Buriola. Nasal symptoms, hemodynamic parameters and nasal and systemic inflammatory profile of sugarcane cutters exposed to biomass burning. 2016. Master's Dissertation - Universidade Estadual Paulista (Unesp). Faculdade de Ciências e Tecnologia. Presidente Prudente Presidente Prudente.