INTRODUCTION: The harvesting of sugarcane preceded by a burning exposes workers to high concentrations of pollutants added to the effects of strenuous physical labor can lead to increased release of inflammatory mediators both nasal and systemic. However, the consequences of exposure to pollution of biomass burning added to the peculiar conditions of employment in the nasal and systemic inflammation are still poorly studied in sugarcane cutters. OBJECTIVES: To assess the impacts of physical stress and air pollution plus the conditions of the working day on nasal and systemic inflammatory markers in sugarcane workers from the West of Sao Paulo State. METHODS: Sugarcane workers, male, aged between 18 and 45 years, smokers and nonsmokers will be evaluated. Evaluations shall be performed in the field planting sugar cane, where volunteers will first be interviewed by questionnaires. In addition to assessments of vital signs, carbon monoxide in exhaled air (exCO), collection of nasal lavage (NL) and blood collection, the following time: (a)the period between harvests; (b) harvest period. All reviews will be conducted in the morning between 7 and 9 A.M.. STATISTICAL ANALYSIS: The normal distribution of the data will be assessed by the Shapiro-Wilk test. For analysis between groups the unpaired t test or Mann- Whitney test and for intragroup analysis , will be used ANOVA for repeated measures followed by Tukey test or Friedman test followed by Dunn's test also depending on the normal distribution of data. Correlations will be evaluated using the Pearson or Spearman coefficients. The level of significance is p<0.05.
News published in Agência FAPESP Newsletter about the scholarship: