Ex-vivo human fibroblasts viability after non-termal atmospheric pressure plasma treatment

• Grant number: 14/04418-2
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: August 01, 2014
• End date: July 31, 2015
• Field of knowledge: Interdisciplinary Subjects
• Principal Investigator: Maria Beatriz Puzzi
• Grantee: Maria Beatriz de Paula Leite Kraft
• Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

The cold atmospheric plasma (CAPs) is the fourth state of matter, which means that it is an ionized gas, obtained at room temperature and atmospheric pressure when energy is supplied to a gas. Its composition is complex, involving chemical (gas's molecules, free radicals, ions and electrons) and physical (Ultra-violet radiation) components. It has been used in the biomedical field since 2000, directly or indirectly. The expectations of good that the CAPs may bring to medical treatments are high and therefore it is necessary to analyze the effects caused by cold atmospheric pressure plasma in ex-vivo dermal fibroblasts. This work aimes to determine if ex-vivo human fibroblasts remain viable after these treatments.