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In vitro analysis of the potential of AmF/NaF/SnCl2 solution to inhibit the progression of erosion on human enamel

Grant number: 14/25514-0
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): February 01, 2015
Effective date (End): December 31, 2015
Field of knowledge:Health Sciences - Dentistry
Principal Investigator:Patricia Moreira de Freitas Costa e Silva
Grantee:Jéssica Laporta Nazello
Home Institution: Faculdade de Odontologia (FO). Universidade de São Paulo (USP). São Paulo , SP, Brazil


Although several studies have shown promising results in AmF/NaF/SnCl2 solution to inhibit the progression of erosion lesion, there is not a consensus on its frequency of use. Then, the objective of this in vitro study is to evaluate the effect of AmF/NaF/SnCl2 solution, used once or twice a day, on the inhibition of erosion progression on human enamel. Fifty human enamel fragments will be selected under surface Knoop Microhardness and profilometry. After, these fragments will be randomly divided into 05 treatment groups (n=10): G1 - distilled water (negative control); G2 - NaF solution (positive control) 1x /day; G3 - NaF solution 2x/day; G4 - AmF /NaF/SnCl2 solution 1x/day; G5 - AmF/NaF/SnCl2 solution 2x/day. The samples will be submitted to a 04-days erosive cycling in which specimens will be immersed, twice a day, for 4 minutes, in citric acid solution (0.65%, pH 3.6). At the end of the erosive cycling, surface wear will be evaluated under optical profilometry. Results will be submitted to normality and homogeneity tests and then to specific statistical analysis (±=5%).

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DA SILVA, CAMILLA VIEIRA; NAZELLO, JESSICA LAPORTA; DE FREITAS, PATRICIA MOREIRA. Frequency of Application of AmF/NaF/SnCl2 Solution and Its Potential in Inhibiting the Progression of Erosion in Human Dental Enamel - An In Vitro Study. ORAL HEALTH & PREVENTIVE DENTISTRY, v. 15, n. 4, p. 365-370, SEP 1 2017. Web of Science Citations: 0.

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