Experimental infection of rainbow trout (Oncorhynchus mykiss) and Atlantic salmon (Salmo salar L.) with piscine reovirus and virus Y

• Grant number: 15/04027-6
• Support Opportunities: Scholarships abroad - Research Internship - Master's degree
• Start date: June 22, 2015
• End date: December 21, 2015
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
• Principal Investigator: Ricardo Luiz Moro de Sousa
• Grantee: Anna Luiza Farias Alencar
• Supervisor: Niels Jørgen Olesen
• Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil
• Institution abroad: Technical University of Denmark (DTU), Denmark
• Associated to the scholarship: 14/03463-4 - Isolation and characterization of frog virus 3-like strain detected in American bull frogs (Lithobates catesbeianus) in São Paulo State, BP.MS

Abstract

Aquaculture is the fastest growing animal food-producing sector and Brazil stands as promising country. However, Brazilian aquaculture struggles with intensification problems. On the other hand, Denmark has a strong position in fish production, ranking fifth in the world's leading exporters of fish products, with aquaculture having an old, well established tradition in the country, with strict regulations and an effective sanitation system. Viral diseases are responsible for major economic losses in fish production worldwide and HSMI (Heart and Skeletal Muscle Inflamation) stands as an important common viral disease in Atlantic salmon. HSMI is characterized by epicarditis, myocarditis and red skeletal muscle inflammation and necrosis. Piscine Reovirus has been appointed as the causative agent of HSMI and its pathogenesis is still unknown. This virus has been detected in farmed fish that did not show clinical signs and also in wild Atlantic salmon. Also, a new virus, preliminary named Virus Y, also a Reovirus, causing disease in farmed rainbow trout in Norway, was notified to the OIE on 2014. In order to assess if this new disease is emerging and should be notified and linked with trade restrictions and if there is a relationship between PRV and virusY, this project aims to conduct a comprehensive study on experimental infections of rainbow trout (Oncorhynchus mykiss) and Atlantic salmon (Salmo salar L.) with piscine reovirus and virus Y. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

HAUGE, HELENA; VENDRAMIN, NICCOLO; TAKSDAL, TORUNN; OLSEN, ANNE BERIT; WESSEL, OYSTEIN; MIKKELSEN, SUSIE SOMMER; ALENCAR, ANNA LUIZA FARIAS; OLESEN, NIELS JORGEN; DAHLE, MARIA KRUDTAA. Infection experiments with novel Piscine orthoreovirus from rainbow trout (Oncorhynchus mykiss) in salmonids. PLoS One, v. 12, n. 7, JUL 5 2017. (15/04027-6)

VENDRAMIN, NICCOLO; ALENCAR, ANNA LUIZA FARIAS; IBURG, TINE MOESGAARD; DAHLE, MARIA KRUDTAA; WESSEL, OYSTEIN; OLSEN, ANNE BERIT; RIMSTAD, ESPEN; OLESEN, NIELS JORGEN. Piscine orthoreovirus infection in Atlantic salmon (Salmo salar) protects against subsequent challenge with infectious hematopoietic necrosis virus (IHNV). VETERINARY RESEARCH, v. 49, MAR 13 2018. (15/04027-6)