Bi-functional catalyst for the Morita-Baylis-Hillman: new applications

• Grant number: 14/26027-5
• Support Opportunities: Scholarships abroad - Research Internship - Scientific Initiation
• Start date: September 14, 2015
• End date: December 13, 2015
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Organic Chemistry
• Principal Investigator: Fernando Antonio Santos Coelho
• Grantee: Laís Vaz Acconcia
• Supervisor: Alberto Baldoire Moyano
• Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Institution abroad: Universitat de Barcelona (UB), Spain
• Associated to the scholarship: 13/24386-5 - Syntheis and evaluation of the pharmacological potential of Pyrazolones and Pyrazolidinones, from Morita-Baylis-Hillman adducts, BP.IC

Abstract

This project of research is aimed at exploring new applications for a new bi-functional catalyst. We intend to use this new catalyst in th eMorita-Baylis-Hillman (MBH) reaction with a-keto esters and for the direct formation of indolizines from MBH adducts prepared from 2-pyridinecarboxyaldehydes. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ZEOLY, LUCAS A.; ACCONCIA, LAIS V.; RODRIGUES JR, MANOEL T.; SANTOS, HUGO; CORMANICH, RODRIGO A.; PANIAGUA, JUAN C.; MOYANO, ALBERT; COELHO, FERNANDO. One-pot organocatalyzed synthesis of tricyclic indolizines. ORGANIC & BIOMOLECULAR CHEMISTRY, v. 21, n. 17, p. 15-pg., 2023-04-14. (13/07600-3, 14/26027-5, 13/24386-5, 18/02611-0, 15/00975-7, 15/09205-0)