Description of clinical and demographic characteristics of patients with Diabetes Mellitus type 2 incident and prevalent in an outpatient clinic of conservative treatment of chronic renal disease

• Grant number: 15/06794-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: October 01, 2015
• End date: September 30, 2016
• Field of knowledge: Health Sciences - Collective Health - Public Health
• Principal Investigator: Maria Eugênia Fernandes Canziani
• Grantee: Victória Cabral Silveira Monteiro de Godoy
• Host Institution: Escola Paulista de Medicina (EPM). Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. São Paulo , SP, Brazil

Abstract

Diabetes Mellitus type 2 (DM2) is considered a public health problem of high economic impact mainly in developing countries such as Brazil. The chronic complications of diabetes, especially cardiovascular and kidney diseases are the main causes of the high rates of morbidity and mortality observed in this population. The treatment of diabetes in CKD patients is mandatory but constitutes a great challenge mainly due to the complexity of glucose homeostasis changes that occur as renal function decreases. The maintenance of glycated hemoglobin (HbA1c) values lower 7% has been suggested to slow CKD progression, decrease albuminuria appearance and nephropathy progression. However, episodes of hypoglycemia were more frequent in diabetic patients with CKD which is related to higher mortality. It is expected in this study to describe the clinical and laboratorial characteristics of DM population, including antidiabetic treatments information and to evaluate the relationship between glycemic control and the stages of CKD. This study will provide data that will help the improvement of strategies of care at the Ambulatório de Tratamento Conservador da Doença Renal Crônica da Disciplina de Nefrologia da UNIFESP. In this retrospective study all CKD patients with DM2 that were seen in the clinic during 2014 will constitute the study sample.