Structured systems by self-assemble of nanoparticles with charged protein molecules

• Grant number: 16/01940-5
• Support type: Scholarships abroad - Research Internship - Post-doctor
• Effective date (Start): April 29, 2016
• Effective date (End): April 28, 2017
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Physical-Chemistry
• Principal researcher: Emerson Rodrigues de Camargo
• Grantee: Luiz Fernando Gorup
• Supervisor abroad: Nicholas A. Kotov
• Home Institution: Centro de Ciências Exatas e de Tecnologia (CCET). Universidade Federal de São Carlos (UFSCAR). São Carlos , SP, Brazil
• Research place: University of Michigan, United States
• Associated to the scholarship: 13/23572-0 - Nanostructured hybrid materials by self-assembly of nanoparticles induced by biomolecules, BP.PD

Abstract

The self-organization of inorganic nanoparticles (NPs) using proteins for to build suprastructures has received special attention in the last few years due to the large variety of available components and a large family hybrid material. It is a promising strategy to obtain materials with properties of great scientific and technological interest as optical devices, potential analytical, biosensors, energy storage, drug delivery systems, and high strength materials. There are numerous examples of structured systems employing DNA, proteins, peptides and aminoacids. In this context, the connection between biotechnology with materials chemistry has been beneficial in several technological areas, such as catalysis, health and sensor development. Thus, the present project is focused in the formation of self-assembly of metal nanoparticles (NPs) with cytochrome C protein (Cyt c) in order to obtain spherical supraparticles with a narrow size distribution. Also, it will be analyzed the effect of supraparticle diameters on the assembly conditions. Also establish a protocol by the fabrication of self-assembly of gold nanoparticles on surfaces with the composition (Al2O3, SiO2, Si, polymer), structure and morphology controlled (plates, wires, tubes). In this study, it is expected the controlled synthesis of self-assembly nanoparticles at microscale superstructures with distinct geometries from biological macromolecules. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

GORUP, LUIZ FERNANDO; PERLATTI, BRUNO; KUZNETSOV, ALEKSEY; NASCENTE, PEDRO AUGUSTO DE PAULA; WENDLER, EDISON PEREVALO; DOS SANTOS, ALCINDO A.; PADILHA BARROS, WILLYAM ROGER; SEQUINEL, THIAGO; TOMITAO, ISABELA DE MACEDO; KUBO, ANDRESSA MAYUMI; LONGO, ELSON; CAMARGO, EMERSON RODRIGUES. Stability of di-butyl-dichalcogenide-capped gold nanoparticles: experimental data and theoretical insights. RSC ADVANCES, v. 10, n. 11, p. 6259-6270, FEB 12 2020. Web of Science Citations: 0.