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Effect of toothpastes of new technology in the hydraulic conductivity to the erosive challenge in dentine

Grant number: 15/18755-3
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): March 01, 2016
Effective date (End): December 31, 2016
Field of knowledge:Health Sciences - Dentistry - Dental Clinics
Principal researcher:Sergio Kiyoshi Ishikiriama
Grantee:Camila Correa da Silva Braga de Melo
Home Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil


Comprehension that the occlusive action of dentinal tubules is able to reduce dentin hypersensitivity has motivated the introduction of agents with different technologies for this function. This in vitro study aims to compare toothpaste to a control group in relation to remineralizing / occlusive ability to dentin, through the hydraulic conductivity (CH). Samples will be randomized and allocated among treatment groups: D (control) - Duraphat Varnish 22600 ppm F; P - Prevident® 5000 Plus (5000 ppm F, Colgate); C - Clinpro® 5000 ppm F (3M / ESPE) + tricalcium phosphate; S - Colgate Sensitive Pro-Alívio® 1450 ppm F + potassium citrate; N - Colgate Neutraçúcar® 1450 ppm F + 1.5% arginine; T - Colgate Total 12 (conventional concentration 1450 ppm F). The application of each agent is performed according to the protocol of each manufacturer. For preparation of specimens, extracted third molars will be cleaned and kept in thymol 0.1%. For CH analysis (n = 8), dentin disks of the central portion of approximately 1.5 mm thickness are obtained to then be prepared by 0.90 + 0.1 mm. The disks are processed in sequence with liquid phosphoric acid 37% (maximum permeability), smear layer (minimum permeability), treatment and challenge with hydrochloric acid 6%, the reading being performed CH (Flodec). The data will be tabulated and analyzed statistically. (AU)

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