Physical activity, risk factors for metabolic syndrome and healthcare expenditures among users of the Brazilian national health system: 8-year longitudinal study

• Grant number: 15/17777-3
• Support type: Scholarships in Brazil - Doctorate
• Effective date (Start): June 01, 2016
• Effective date (End): July 31, 2019
• Field of knowledge: Health Sciences - Collective Health - Public Health
• Principal researcher: Henrique Luiz Monteiro
• Grantee: Ítalo Ribeiro Lemes
• Home Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil
• Associated scholarship(s): 16/11140-6 - Physical activity, obesity and risk factors for metabolic syndrome in the brazilian public health system: a longitudinal study, BE.EP.DR

Abstract

Background: Changes in lipid profile, fasting blood glucose and blood pressure, along with abdominal obesity, are risk factors for the development of metabolic syndrome (MetS), increasing the chances of cardiovascular disease and type 2 diabetes mellitus, therefore, it is an important indicator of risk for premature death. These clinical signs are directly related to low levels of physical activity (PA), a very common condition in the population of developed and developing countries. Although longitudinal researches allow to establish a relationship of cause and effect, this study design is still little developed in Brazil, especially when it concerns the relationship between PA and development of chronic diseases such as MetS. Aim: To investigate the relationship between physical activity, occurrence of risk factors for metabolic syndrome and complications in users of the public health system in a historical series study of eight-year. Methods: A random sample stratified by age (e 50 years old) was selected among the main Basic Health Units in each region (north, south, east, west and center) of the city of Bauru, Sao Paulo. The sample size calculation indicated the need for follow-up of 960 patients. Through surveys by directed interview, physical examination and medical records analysis will be obtained data on the occurrence of risk factors for MetS, physical activity, complications and hospitalizations, economic status, education, smoking and nutritional status. This proposal is being developed in five stages distributed between 2009 and 2017. In the first stage (2009-2010) each patient attended to his Basic Health Unit (BHU) of origin where it was held a interview, physical examination and review of medical records. In the second (2011-2012) and third stages (2013-2014) the interviews took place by telephone, while the data collection in clinical records followed the same routine of the first step. In the fourth (2015) and fifth (2017) stages, the same procedures as the first stage will be adopted, with face-to-face interviews and physical evaluation. In the statistical analysis, because it is a historical series study, the main analysis will be conducted using the Cox regression, hazard ratios (HR) and their respective confidence intervals of 95% (HRIC95%). Statistical significance will be set at values below 5%.

Scientific publications

(13)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

LEMES, ITALO RIBEIRO; PINTO, RAFAEL ZAMBELLI; TURI LYNCH, BRUNA CAMILO; CODOGNO, JAMILE SANCHES; OLIVEIRA, CRYSTIAN BITENCOURT; ROSS, LEANNA M.; FERNANDES, ROMULO ARAUJO; MONTEIRO, HENRIQUE LUIZ. The Association Between Leisure-time Physical Activity, Sedentary Behavior, and Low Back Pain A Cross-sectional Analysis in Primary Care Settings. SPINE, v. 46, n. 9, p. 596-602, MAY 1 2021. Web of Science Citations: 0.

LEMES, ITALO RIBEIRO; SUI, XUEMEI; TURI-LYNCH, BRUNA CAMILO; LEE, DUCK-CHUL; BLAIR, STEVEN N.; FERNANDES, ROMULO ARAUJO; CODOGNO, JAMILE SANCHES; MONTEIRO, HENRIQUE LUIZ. Sedentary behaviour is associated with diabetes mellitus in adults: findings of a cross-sectional analysis from the Brazilian National Health System. JOURNAL OF PUBLIC HEALTH, v. 41, n. 4, p. 742-749, DEC 2019. Web of Science Citations: 4.

LEMES, ITALO R.; FERNANDES, ROMULO A.; TURI-LYNCH, BRUNA C.; CODOGNO, JAMILE S.; DE MORAIS, LUANA C.; KOYAMA, KELLY A. K.; MONTEIRO, HENRIQUE L. Metabolic Syndrome, Physical Activity, and Medication-Related Expenditures: A Longitudinal Analysis. JOURNAL OF PHYSICAL ACTIVITY & HEALTH, v. 16, n. 10, p. 830-835, OCT 2019. Web of Science Citations: 1.

KIKUTI-KOYAMA, KELLY AKEMI; MONTEIRO, HENRIQUE LUIZ; LEMES, ITALO RIBEIRO; DE MORAIS, LUANA CAROLINA; FERNANDES, ROMULO; TURI-LYNCH, BRUNA; CODOGNO, JAMILE. Impact of type 2 diabetes mellitus and physical activity on medication costs in older adults. INTERNATIONAL JOURNAL OF HEALTH PLANNING AND MANAGEMENT, AUG 2019. Web of Science Citations: 0.

TURI-LYNCH, BRUNA C.; MONTEIRO, HENRIQUE LUIZ; FERNANDES, ROMULO ARAUJO; SUI, XUEMEI; LEMES, ITALO RIBEIRO; CODOGNO, JAMILE SANCHES. Impact of sports participation on mortality rates among Brazilian adults. JOURNAL OF SPORTS SCIENCES, v. 37, n. 13, p. 1443-1448, JUL 3 2019. Web of Science Citations: 1.

BRIANI, RONALDO VALDIR; FERREIRA, AMANDA SCHENATTO; PAZZINATTO, MARCELLA FERRAZ; PAPPAS, EVANGELOS; SILVA, DANILO DE OLIVEIRA; DE AZEVEDO, FABIO MICOLIS. Infographic. What interventions can improve quality of life or psychosocial factors of individuals with knee osteoarthritis? A systematic review with meta-analysis of primary outcomes from randomised controlled trials. BRITISH JOURNAL OF SPORTS MEDICINE, v. 53, n. 14, p. 901-902, JUL 2019. Web of Science Citations: 0.

LEMES, ITALO RIBEIRO; SUI, XUEMEI; TURI-LYNCH, BRUNA CAMILO; BLAIR, STEVEN N.; FERNANDES, ROMULO ARAUJO; CODOGNO, JAMILE SANCHES; MONTEIRO, HENRIQUE LUIZ. Association of TV Viewing and All-Cause Mortality in Older Adults With Hypertension: A 6-Year Longitudinal Study. JOURNAL OF AGING AND PHYSICAL ACTIVITY, v. 27, n. 3, p. 378-383, JUN 2019. Web of Science Citations: 2.

LEMES, I. R.; SUI, X.; FERNANDES, R. A.; BLAIR, S. N.; TURI-LYNCH, B. C.; CODOGNO, J. S.; MONTEIRO, H. L. Association of sedentary behavior and metabolic syndrome. PUBLIC HEALTH, v. 167, p. 96-102, FEB 2019. Web of Science Citations: 1.

LEMES, ITALO RIBEIRO; SUI, XUEMEI; FRITZ, STACY L.; BEATTIE, PAUL F.; LAVIE, CARL J.; TURI-LYNCH, BRUNA CAMILO; BLAIR, STEVEN N. Cardiorespiratory Fitness and Risk of All-Cause, Cardiovascular Disease, and Cancer Mortality in Men With Musculoskeletal Conditions. JOURNAL OF PHYSICAL ACTIVITY & HEALTH, v. 16, n. 2, p. 134-140, FEB 2019. Web of Science Citations: 0.

BRIANI, RONALDO VALDIR; FERREIRA, AMANDA SCHENATTO; PAZZINATTO, MARCELLA FERRAZ; PAPPAS, EVANGELOS; SILVA, DANILO DE OLIVEIRA; DE AZEVEDO, FABIO MICOLIS. What interventions can improve quality of life or psychosocial factors of individuals with knee osteoarthritis? A systematic review with meta-analysis of primary outcomes from randomised controlled trials. BRITISH JOURNAL OF SPORTS MEDICINE, v. 52, n. 16, p. 1031+, AUG 2018. Web of Science Citations: 19.

LEMES, ITALO RIBEIRO; TURI-LYNCH, BRUNA CAMILO; CAVERO-REDONDO, IVAN; LINARES, STEPHANIE NOGUEIRA; MONTEIRO, HENRIQUE LUIZ. Aerobic training reduces blood pressure and waist circumference and increases HDL-c in metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, v. 12, n. 8, p. 580-588, AUG 2018. Web of Science Citations: 8.

OLIVEIRA, CRYSTIAN B.; ELKINS, MARK R.; LEMES, ITALO RIBEIRO; SILVA, DANILO DE OLIVEIRA; BRIANI, RONALDO V.; MONTEIRO, HENRIQUE LUIZ; DE AZEVEDO, FABIO MICOLIS; PINTO, RAFAEL ZAMBELLI. A low proportion of systematic reviews in physical therapy are registered: a survey of 150 published systematic reviews. BRAZILIAN JOURNAL OF PHYSICAL THERAPY, v. 22, n. 3, p. 177-183, MAY-JUN 2018. Web of Science Citations: 3.

TURI, B. C.; MONTEIRO, H. L.; LEMES, I. R.; CODOGNO, J. S.; LYNCH, K. R.; ASAHI MESQUITA, C. A.; FERNANDES, R. A. TV viewing time is associated with increased all-cause mortality in Brazilian adults independent of physical activity. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, v. 28, n. 2, p. 596-603, FEB 2018. Web of Science Citations: 5.

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

LEMES, Ítalo Ribeiro. Atividade física, comportamento sedentário, síndrome metabólica e mortalidade : estudo longitudinal com pacientes do Sistema Único de Saúde. 2019. 166 f. Doctoral Thesis - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Ciências e Tecnologia..