Retrospective study of the odontogenic tumors: clinicopathological features

• Grant number: 16/07399-4
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: August 01, 2016
• End date: July 31, 2017
• Field of knowledge: Health Sciences - Medicine - Pathological Anatomy and Clinical Pathology
• Principal Investigator: Fernanda Viviane Mariano Brum Corrêa
• Grantee: Suzana Shinomia
• Host Institution: Faculdade de Ciências Médicas (FCM). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil

Abstract

Odontogenic tumors (TO) consist of a heterogeneous group of lesions with various clinical and histological behavior, derived from epithelium, ectomesenchyme and/or mesenchymal apparatus dental or their remnants. Involve from tumor malformations (hamartomas) to neoplasms benign and metastatic malignancies. They are rare, compounding only 1% of tumors of the maxillofacial region. This way, specific protocols and therapeutic guidelines are not available. Early diagnosis and proper treatment planning contribute to a better prognosis. This study aims to carry out a retrospective clinicopathological analysis of TOs, and try to suggest possible risk factors and analyze the different types of treatment made with their answers. For this we will make a retrospective study of patients who developed TOs from 1980 and were treated at our institution. Clinicopathological data, image details and related treatment will be collected from medical records with standardized form for the study. Histopathological analysis of the H&E slides will be held for histological confirmation of tumor types. According with doubts in relation to pathogenesis and series of OTs in the world, this study intends clarify possible causal factors that can be studied and to contribute to a greater understanding of these tumors.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MARIANO, FERNANDA VIVIANE; GONDAK, ROGERIO OLIVEIRA; SCARINI, JOAO FIGUEIRA; ALBINO DA SILVA, EDUARDO CAETANO; CARAVINA, GISELE; SCAPULATEMPO-NETO, CRISTOVAM; ALMEIDA, OSLEI PAES; ALTEMANI, ALBINA; TAYLOR, ADALBERTO MOSQUEDA. Odontogenic Carcinoma With Dentinoid in Long-Term Follow-up With 2 Recurrences. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, SEP 2019. (17/00831-0, 16/07399-4)

MARIANO, FERNANDA VIVIANE; GONDAK, ROGERIO OLIVEIRA; SCARINI, JOAO FIGUEIRA; ALBINO DA SILVA, EDUARDO CAETANO; CARAVINA, GISELE; SCAPULATEMPO-NETO, CRISTOVAM; ALMEIDA, OSLEI PAES; ALTEMANI, ALBINA; TAYLOR, ADALBERTO MOSQUEDA. Odontogenic Carcinoma With Dentinoid in Long-Term Follow-up With 2 Recurrences. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, v. 28, n. 2, p. 7-pg., 2019-09-05. (16/07399-4, 17/00831-0)