Selective cofactor regeneration mediated by enzymes immobilized on designed nanopa...
| Grant number: | 16/12311-9 |
| Support type: | Scholarships in Brazil - Post-Doctorate |
| Effective date (Start): | September 01, 2016 |
| Effective date (End): | May 31, 2018 |
| Field of knowledge: | Physical Sciences and Mathematics - Physics |
| Principal Investigator: | Osvaldo Novais de Oliveira Junior |
| Grantee: | Jorge Ricardo Mejía Salazar |
| Home Institution: | Instituto de Física de São Carlos (IFSC). Universidade de São Paulo (USP). São Carlos , SP, Brazil |
| Associated research grant: | 13/14262-7 - Nanostructured films from biologically-relevant materials, AP.TEM |
Abstract The Group of Polymer Bernhard Gross, the Institute of Physics of São Carlos (IFSC / USP) has for years developing biosensors for which materials and architectures are selected empirically based on experimental data. In this project, we will study the biosensor design exploiting plasmonic resonances from a theoretical point of view. More specifically, we will consider biosensors where the plasmonic effects can be altered by a static magnetic field applied across. New structures are proposed for biosensors by optimizing the plasmonic effects using numerical techniques such as the method of transfer matrix (TMM) and the method of finite differences in the time domain (FDTD) method. The TMM is suitable for systems with flat surfaces, while the FDTD technique is applicable even for very complex geometries. Various configurations for the excitation of surface plasmon polaritons-(SPPs) in thin films and multilayer systems will be considered. The main objective is the design of biosensors based on the magneto-optical Kerr effect cross (TMOKE), including miniature versions as a lab-on-chip to detect diseases such as cancer. The results of this theoretical work will be used by the experimental team in the group to make the corresponding biosensors. | |