Influence of host's evolutionary history on parasite and host fitness: a case study of drosophilids and Drosophila a virus

• Grant number: 16/09934-4
• Support Opportunities: Scholarships in Brazil - Master
• Start date: November 01, 2016
• End date: August 31, 2018
• Field of knowledge: Biological Sciences - Genetics - Animal Genetics
• Principal Investigator: Rodrigo Cogni
• Grantee: Camila Souza Beraldo
• Host Institution: Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 13/25991-0 - Ecological genomics of insects: climate adaptations and evolution of ecological interactions, AP.JP
• Associated scholarship(s): 17/11774-8 - Phylogenetic mixed models and host-parasite interaction: implications of hosts phylogeny on the fitness of the interacting species, BE.EP.MS

Abstract

Coevolution is the evolutionary process that drives phenotypic changes in interacting species. Although coevolution had been very well studied in the last decades, few studies show empiric evidences for coevolution. Theoretical studies suggest that, in order to understand coevolution, it is necessary to study the coevolutionary mechanisms that causes reciprocal selection, and not only patterns of geographic variation. In this project, we will study the mechanisms for reciprocal selection, using the interaction between drosophilids and Drosophila A virus. Our aim is to study the influence of host's phylogeny on DAV and host fitness. We will investigate the variation in the resistance of 48 species of drosophilids to DAV and the variation of DAV's virulence within different hosts. The resistance will be measured by DAV's viral load, which will be done by real time quantitative PCR after reaction of reverse transcriptase, and the virulence will be measured by flies' mortality and fecundity after DAV infection. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ANDRÉ C. PIMENTEL; CAMILA S. BERALDO; RODRIGO COGNI. Host-shift as the cause of emerging infectious diseases: Experimental approaches using Drosophila-virus interactions. GENETICS AND MOLECULAR BIOLOGY, v. 44, n. 1, 2020-11-23. (16/09934-4, 15/08307-3, 17/11774-8, 13/25991-0)

PIMENTEL, ANDRE C.; BERALDO, CAMILA S.; COGNI, RODRIGO. Host-shift as the cause of emerging infectious diseases: Experimental approaches using Drosophila-virus interactions. GENETICS AND MOLECULAR BIOLOGY, v. 44, n. 1, 1, 2021. (15/08307-3, 17/11774-8, 16/09934-4, 13/25991-0)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

BERALDO, Camila Souza. Variation in host susceptibility to different pathogens: an experimental and phylogenetic study of Drosophila-viruses. 2018. Master's Dissertation - Universidade de São Paulo (USP). Instituto de Biociências (IBIOC/SB) São Paulo.