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Are men and women with bronchiectasis different clinically and functionally?

Grant number: 16/20518-2
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): April 01, 2017
Effective date (End): December 31, 2018
Field of knowledge:Health Sciences - Physiotherapy and Occupational Therapy
Principal Investigator:Simone Dal Corso
Grantee:Tiago Pereira de Freitas
Host Institution: Universidade Nove de Julho (UNINOVE). Campus Vergueiro. São Paulo , SP, Brazil


There is a growing interest in knowing the differences between genders in patients with chronic respiratory diseases. It has already been described that women have a higher prevalence of cases of pulmonary hypertension, Cor Pulmonale, lung infections and lung cancer in nonsmokers. It is interesting to note that the diseases affecting airways such as asthma in adulthood, cystic fibrosis, chronic obstructive pulmonary disease (COPD) and bronchiectasis are also more prevalent in women. However, it is not yet known if clinical and functional characteristics are different when comparing males and females. Aim: To evaluate the clinical and functional differences between men and women with bronchiectasis. Methods: This is a cross-sectional study with adults with bronchiectasis and clinically stable. Patients will be excluded as follows: current smokers, other chronic pulmonary diseases, cardiovascular diseases and patients unable to perform the tests due to musculoskeletal limitations. Outcomes to be evaluated: spirometry, functional capacity (incremental shuttle walk test), quality of life (St. George's Respiratory Questionnaire), Dyspnea (Medical Research Council scale) and physical activity in daily life measured by a pedometer. Expected results: It is possible that men and women present with clinical and functional differences. If confirmed these findings, it will be possible to develop treatment and more accurate rehabilitation strategies according to sex. (AU)

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