Effect of botulinum toxin a in the abdominal wall in transplant patients with incisional hernia: preoperative management

• Grant number: 16/20446-1
• Support type: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): March 01, 2017
• Effective date (End): December 31, 2017
• Field of knowledge: Health Sciences - Medicine - Surgery
• Principal Investigator: Alberto Luiz Monteiro Meyer
• Grantee: Lucas Torres Oliveira
• Home Institution: Faculdade de Medicina (FM). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

According to the literature, between 6% and 25% of all liver transplant patients are likely to purchase incisional hernia and eventually face the issue of undergoing surgical hernia surgery. In the population of transplant patients, obesity, advanced age, diabetes mellitus, primary liver disease, and type of immunosuppression are known risk factors for the development of incisional hernias. This study will examine the effect of muscle stretching of the abdominal wall and relaxation induced by botulinum toxin A, in order to facilitate the fascial closure allowing the complex ventral hernia repair after liver transplantation. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

OLIVEIRA, LUCAS TORRES; ESSU, FELIPE FUTEMA; ANTUNES DE MESQUITA, GUSTAVO HELUANI; JARDIM, YURI JUSTI; IUAMOTO, LEANDRO RYUCHI; SUGUITA, FABIO YUJI; MARTINES, DIEGO RAMOS; NII, FERNANDA; WAISBERG, DANIEL REIS; MEYER, ALBERTO; ANDRAUS, WELLINGTON; CARNEIRO D'ALBUQUERQUE, LUIZ AUGUSTO. Component separation of abdominal wall with intraoperative botulinum A presents satisfactory outcomes in large incisional hernias: a case report. INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, v. 41, p. 99-104, 2017. Web of Science Citations: 1.