The main anabolic stimuli for hypertrophy are physical exercise and dietary protein intake. Both act synergically by increasing the muscular protein synthesis (MPS) and inhibiting and/or decreasing the muscular protein degradation (MPD). This process leads to a positive protein balance that, if chronically sustained, may result in gain of muscle mass. Nonetheless, the response generated in the MPS obtained from protein intake depends on several aspects, such as dose, timing (from exercise) and protein source. In regards to dose and timing, their effects are vastly described and confirmed in the literature, while studies on protein source are not yet conclusive even though the science suggesting that there are differences in the potential optimization of anabolic stimuli induced by exercise, including when comparing between high biological value proteins. Therefore, the aim of this study is to investigate the impact of the dietary protein source on adaptations induced by long-term resistance training. For this purpose, vegan subjects (n=20) - exclusively plant-based proteins adherents - and omnivores subjects (n=20) - plant and animal-based proteins adherents - will be equated by the total amount of protein intake/day, and then submitted to a resistance training program in order to measure and evaluate their gain of muscle mass and strength at the end of the period. A nutritional assessment as well as a dietetic control will be carried out through 24-h diet recalls. With these data, both groups (VEG and OMN) will be supplemented with protein in order to equally match the amount of protein intake until they reach 1,7 g/kg/day each, differing only in the protein source. The individuals will then be submitted to a 12-week resistance training program and diet control. It will be determined the data of one-repetition maximum (1-RM) leg press strength, vastus lateralis cross-sectional area and body composition assessment. The data will be treated for repeated measures having group and time assumed as fixed factors and individuals as random factor. The level of significance will be pre-set at p<0,05. (AU)
News published in Agência FAPESP Newsletter about the scholarship:
DE ANDRADE, ISABEL THOMAZI;
GOMES, RODRIGO LEITE;
ARTIOLI, GUILHERME GIANNINI;
PHILLIPS, STUART M.;
Leucine Supplementation Has No Further Effect on Training-induced Muscle Adaptations.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE,
Web of Science Citations: 0.
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