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Study and evaluation of the influence of different inocules on the antibiotic sulfamethoxazole removal in anaerobic structured bed reactor

Grant number: 17/18718-6
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): October 01, 2017
Effective date (End): September 30, 2018
Field of knowledge:Engineering - Sanitary Engineering
Principal Investigator:Marcelo Zaiat
Grantee:Caroline Fernanda Sella
Home Institution: Escola de Engenharia de São Carlos (EESC). Universidade de São Paulo (USP). São Carlos , SP, Brazil
Associated research grant:15/06246-7 - Biorefinery concept applied to biological wastewater treatment plants: environmental pollution control coupled with material and energy recovery, AP.TEM

Abstract

Antibiotics are widely used in human and veterinary medicine and only partially degraded in sewage treatment plants, which, even with their low concentrations in water (between ng/L and ¼g/L), creates the opportunity for multiple potential sources of contamination, such as domestic sewage treatment plants and extensive breeding sites. In addition, antibiotics have the ability to alter the microbial community structure, promoting the development of resistant human pathogens. Sulfamethoxazole (SMX) is a bacteriostatic antibacterial agent that, from the synthesis of folic acid, interferes with susceptible bacteria. It presents a broad spectrum of activity that has been limited by the development of resistance in the target organisms, while being one of the most commonly found antibiotics in aquatic environments. Therefore, in addition to exploring the study of anaerobic biodegradation processes of this compound in anaerobic structured bed reactor, this project proposes the evaluation of the influence of three different inocula sources - sewage treatment plant sludge, brewery sludge and poultry slaughtering sludge - on the SMX removal and its impact on methanogenesis, since the inocula present different compositions. (AU)