Screening of compounds with potential antiviral action against alphavirus and orthobunyavirus

• Grant number: 17/23004-2
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• Start date: February 01, 2018
• End date: July 20, 2018
• Field of knowledge: Biological Sciences - Microbiology
• Principal Investigator: Luiz Tadeu Moraes Figueiredo
• Grantee: Aline Lavado Tolardo
• Supervisor: Colleen B. Jonsson
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Institution abroad: University of Tennessee Health Science Center (UTHSC), United States
• Associated to the scholarship: 16/17457-1 - Compounds screening with potential antiviral action against Alphaviruses and Orthobunyaviruses, BP.DR

Abstract

Alphavirus and orthobunyavirus are important arboviruses causing public health problems in Brazil, producing epidemics with great economic and social impact and great economic losses. As there is no specific antiviral treatment for these viruses, medicaments are used to combat the symptoms and signs manifested by the disease in mild and moderate cases. This PhD research project proposes to search, in an initial step, for possible antiviral compounds against these arboviruses of significant importance in Brazil. (AU)