Photodynamic therapy is a treatment for diverse superficial lesures and cancers, being a very attractive method because of its specificity and selectivity. The therapy consists in applying a photosensitizer (PS) and a light with specific wavelength for each PS utilized. Various molecules with tendency to excite and transfer intramolecular electrons, yielding singlet oxygen, like tiazines, Phthalocyanines and Xanthenes can be used as photosensitizers. This project has the purpose to study the ground and excited states of xanthene molecules and derivatives using the Density Functional Theory, propounding the viability of new molecules to the photodynamic therapy.
News published in Agência FAPESP Newsletter about the scholarship: