Spatial-temporal dynamics of yellow fever virus in the state of São Paulo, Brazil

• Grant number: 18/23364-1
• Support Opportunities: Scholarships abroad - Research Internship - Post-doctor
• Start date: April 01, 2019
• End date: August 31, 2019
• Field of knowledge: Biological Sciences - Ecology - Applied Ecology
• Principal Investigator: Jean Paul Walter Metzger
• Grantee: Paula Ribeiro Prist
• Supervisor: Jonathan Rhodes
• Host Institution: Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Institution abroad: University of Queensland, Brisbane (UQ), Australia
• Associated to the scholarship: 17/11666-0 - Yellow fever: transmission risk due to landscape changes and climate alterations, BP.PD

Abstract

Yellow fever is a hemorrhagic fever that affects about 200,000 people annually in the endemic regions. It is transmitted in its wild cycle through the bite of infected Haemagogus spp. and Sabethes spp. mosquitos, which are arboreal and abundant in fragmented and degrades landscapes. Connectivity among habitats is important for a wide range of ecological processes, including disease transmission, once it describes the degree to which an environment´s spatial configuration facilitates or impedes vectors flows. However, our understanding of how landscape connectivity modulates yellow fever virus dispersion remains limited. To understand these effects, nonhuman primates constitute a privileged study element, once they are the main hosts of the virus and serve as an alert to the health agencies about the circulation of the agent. Here we will use circuit theory to model yellow fever virus flow in 30 municipalities of the state of São Paulo, Brazil. In the first step we will create a cost surface that represent permeability of the landscape to movement for yellow fever virus. For this we will use as basis the land use land cover map created by The Brazilian Sustainable Development Foundation, for the year of 2013, and which have six classes: water, urban, agricultural, forest, natural non-forest and forestry areas. Then we will use epizootic coordinates events through São Paulo state as nodes and circuit theory to connect pairs of nodes. The date of each event will be used in order to understand the temporality of the virus dispersal. With the resistance values generate by the Circuit Scape program, we will calculate the least expensive route between nodes, creating a map of connectivity. Evaluating contributions of these factors to yellow fever risk may enable predictions of future outbreaks and is critical to development of effective public health strategies. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

PRIST, PAULA RIBEIRO; PRADO, AMANDA; TAMBOSI, LEANDRO REVERBERI; UMETSU, FABIANA; BUENO, ADRIANA DE ARRUDA; PARDINI, RENATA; METZGER, JEAN PAUL. Moving to healthier landscapes: Forest restoration decreases the abundance of Hantavirus reservoir rodents in tropical forests. Science of The Total Environment, v. 752, JAN 15 2021. (13/23457-6, 18/23364-1, 13/12515-5, 17/11666-0)

BOESING, ANDREA LARISSA; PRIST, PAULA RIBEIRO; BARRETO, JULIA; HOHLENWERGER, CAMILA; MARON, MARTINE; RHODES, JONATHAN R.; ROMANINI, EDUARDA; TAMBOSI, LEANDRO REVERBERI; VIDAL, MARIANA; METZGER, JEAN PAUL. Ecosystem services at risk: integrating spatiotemporal dynamics of supply and demand to promote long-term provision. ONE EARTH, v. 3, n. 6, p. 704-713, DEC 18 2020. (17/50015-5, 17/26093-6, 17/11666-0, 18/23364-1, 19/13802-4, 15/24802-4)

METZGER, JEAN PAUL; BUSTAMANTE, MERCEDES M. C.; FERREIRA, JOICE; FERNANDES, GERALDO WILSON; LIBRAN-EMBID, FELIPE; PILLAR, VALERIO D.; PRIST, PAULA R.; RODRIGUES, RICARDO RIBEIRO; VIEIRA, IMA CELIA G.; OVERBECK, GERHARD E.; et al. Why Brazil needs its Legal Reserves. PERSPECTIVES IN ECOLOGY AND CONSERVATION, v. 17, n. 3, p. 91-103, JUL-SEP 2019. (13/50718-5, 17/11666-0, 18/23364-1)

RIBEIRO PRIST, PAULA; REVERBERI TAMBOSI, LEANDRO; FILIPE MUCCI, LUIS; PINTER, ADRIANO; PEREIRA DE SOUZA, RENATO; DE LARA MUYLAERT, RENATA; ROGER RHODES, JONATHAN; HENRIQUE COMIN, CESAR; DA FONTOURA COSTA, LUCIANDO; LANG D'AGOSTINI, TATIANA; et al. Roads and forest edges facilitate yellow fever virus dispersion. JOURNAL OF APPLIED ECOLOGY, v. 59, n. 1, OCT 2021. (18/09125-4, 18/14389-0, 15/22308-2, 18/23364-1, 17/11666-0)