Assessment of body composition change by bioelectrical impedance: application in chronic kidney disease

• Grant number: 18/18199-1
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): February 01, 2019
• Effective date (End): January 31, 2020
• Field of knowledge: Health Sciences - Nutrition - Nutritional Analysis of Population
• Principal Investigator: Paula Garcia Chiarello
• Grantee: Amanda de Queirós Mattoso Ono
• Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil

Abstract

Chronic kidney disease (CKD) stands out as a global health problem, whose prevalence and incidence rates are high and increasing. Both the pathophysiology of CKD as well as the diverse effects of the available treatments alter the body composition in order to compromise nutritional status. As a consequence, CKD has a high morbimortality rate. Thus, appropriate methods for assessing nutritional status that are low cost and readily available are important as screening tools. On the other hand, spectroscopy multifrequency bioelectrical impedance (BIS) has been highlighted: its application can occur by whole body or segmental analysis. Thus, the objective of this research project is to evaluate the concordance and correlation between body composition change data provided by segmental and total body BIS analysis with those generated by X-ray absorptiometry (DXA) in patients with CKD, after approximately 12 months of the first evaluation. 240 volunteers will be evaluated subdivided equally in each of the groups stratified by the type of treatment: conservative, peritoneal dialysis, hemodialysis and kidney transplantation. The volunteers will be submitted to body evaluation by DXA (reference method) and by BIS, in whole-body and segmental-body methodology. The values will be presented in mean and standard deviation. The Bland-Altman test will be used for concordance analysis and the Pearson correlation coefficient for correlation evaluations (p <0.05).