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Nutritional assessment by specific and classical bioelectrical impedance vector analysis: application in chronic kidney disease

Grant number: 18/18865-1
Support Opportunities:Scholarships in Brazil - Scientific Initiation
Effective date (Start): July 01, 2019
Effective date (End): June 30, 2020
Field of knowledge:Health Sciences - Nutrition - Nutritional Analysis of Population
Principal Investigator:Paula Garcia Chiarello
Grantee:Luísa Maria Diani
Host Institution: Faculdade de Medicina de Ribeirão Preto (FMRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil


Chronic Kidney Disease (CKD) has a high morbimortality rate, strongly related to the presence of muscle depletion and excess fat. Thus, there is a need for adequate and easily applicable methods to the clinical routine to evaluate body composition, allowing the implementation of an early and resolutive intervention. In this context, bioelectrical impedance vector analysis (BIVA) has been highlighted. Thus, the objective of the present study is to evaluate the concordance between the classifications of nutritional status obtained by classical BIVA (cBIVA) and specific BIVA (eBIVA) with those generated by X-ray absorptiometry (DXA) analysis, in CKD patients. Two hundred and forty volunteers will be evaluated subdivided equally in each of the groups stratified by the type of treatment: conservative, peritoneal dialysis, hemodialysis and renal transplantation. The diagnoses of muscle mass depletion, depletion and excess of fat mass and obesity will be obtained by DXA through the analysis of the appendicular lean mass index and the fat mass index, respectively. The bioelectrical parameters of resistance and reactance used in the calculations of BIVAc and BIVAe will be obtained by spectroscopy multifrequency bioelectrical impedance by tetra-polar whole-body methodology. Data will be presented in mean and standard deviation and the kappa correlation coefficient will be used for concordance analysis (p <0.05).

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