Disposable and flexible sensors using polyethylene terephthalate (PET) and a new conductive ink for the detection of estriol in environmental and pharmaceutical samples

• Grant number: 19/04085-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: May 01, 2019
• End date: December 31, 2020
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Physical-Chemistry
• Principal Investigator: Bruno Campos Janegitz
• Grantee: Jefferson Henrique de Souza Carvalho
• Host Institution: Centro de Ciências Agrárias (CCA). Universidade Federal de São Carlos (UFSCAR). Araras , SP, Brazil

Abstract

In recent years, the development of disposable electrochemical electrodes has attracted attention, given its relevant advantages such as good sensitivity, low production cost, large scale production, portability for in situ analysis and miniaturization of the system. In this context, the technique of printed electrodes has been widely used in the electroanalytical for the development of new platforms and in the improvement of their performances. With the objective of developing a conductive ink from a resin not found in the literature for disposable electrochemical sensors - alkyd resin - and graphite, through a disposable sensor with relatively low cost and easy to make, through the technique of screen printing, which will be manufactured an electrode using a substrate from PET bottles. One of the most important female estrogens, along with estrone and 17²-estradiol, is estriol (E3), being produced mainly during pregnancy and used as a medicine for its modular role in various diseases. However, inefficiency in the treatment of hormones in waters and effluents, together with their common pharmacological use, make this an emerging contaminant. The device will be characterized by microscopy, spectroscopy and voltammetry techniques, with subsequent analyzes to detect the female hormone E3, seeking to verify its functionality in water - distribution and environmental - and pharmaceutical samples.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

MAURUTO DE OLIVEIRA, GABRIELA C.; DE SOUZA CARVALHO, JEFFERSON HENRIQUE; BRAZACA, LAIS CANNIATTI; SILVA VIEIRA, NIRTON CRISTI; JANEGITZ, BRUNO CAMPOS. Flexible platinum electrodes as electrochemical sensor and immunosensor for Parkinson's disease biomarkers. BIOSENSORS & BIOELECTRONICS, v. 152, MAR 15 2020. (17/17572-8, 18/07508-3, 19/04085-7, 17/21097-3, 18/19750-3, 17/21898-6)

PRADEL-FILHO, LAURO A.; ANDREOTTI, ISABELA A. A.; CARVALHO, JEFFERSON H. S.; ARAUJO, DIELE A. G.; ORZARI, LUIZ O.; GATTI, ALEXANDRE; TAKEUCHI, REGINA M.; SANTOS, ANDRE L.; JANEGITZ, BRUNO C.. Glass varnish-based carbon conductive ink: A new way to produce disposable electrochemical sensors. SENSORS AND ACTUATORS B-CHEMICAL, v. 305, FEB 15 2020. (16/12697-4, 17/21898-6, 17/21097-3, 19/04085-7)

CARVALHO, JEFFERSON H. S.; GOGOLA, JEFERSON L.; BERGAMINI, MARCIO F.; MARCOLINO-JUNIOR, LUIZ H.; JANEGITZ, BRUNO C.. Disposable and low-cost lab-made screen-printed electrodes for voltammetric determination of L-dopa. SENSORS AND ACTUATORS REPORTS, v. 3, NOV 2021. (19/04085-7, 17/21097-3)