Utilization of layered compounds for intercalation and encapsulation of natural Apocarotenoids

• Grant number: 19/10002-7
• Support Opportunities: Scholarships in Brazil - Master
• Start date: August 01, 2019
• End date: April 30, 2021
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Inorganic Chemistry
• Principal Investigator: Vera Regina Leopoldo Constantino
• Grantee: Lucas Urbano José
• Host Institution: Instituto de Química (IQ). Universidade de São Paulo (USP). São Paulo , SP, Brazil

Abstract

Bixin and norbixin are apocarotenoids and the main components of annatto dye. Such compounds show applications as bactericidal, fungicidal and anticancer agent, antioxidant and radical scavenging activity; however, these compounds present low stability under mild conditions due to their photosensitivity and reactivity towards reactive species found in the air. An approach to enhance the chemical stability consists in intercalate annatto dyes into layered materials such as layered double hydroxides (LDH) and layered hydroxide salts (LHS), or yet encapsulate them inside Pickering Emulsions stabilized by the same layered materials already mentioned. The characterization of apocarotenoids dyes and both layered materials, composed of Zn(II) and Al(III) will be performed by X-ray powder diffraction, UV-vis electronic spectroscopy, infrared and Raman vibrational spectroscopies, solid state nuclear magnetic resonance of 13C and 27Al, thermogravimetric analysis coupled to mass spectrometry, chemical elemental analysis, contact angle measurement, particle size and zeta potential. The emulsions will be visually characterized through an optical microscopy aiming to obtain average particle size and dispersion by means of image treatment. (AU)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

JOSÉ, Lucas Urbano. Natural apocarotenoid and layered double hydroxide organicInorganic hybrid material as a pickering emulsifier. 2021. Master's Dissertation - Universidade de São Paulo (USP). Conjunto das Químicas (IQ e FCF) (CQ/DBDCQ) São Paulo.