Autonomical recovery and celular responses in low intensity resistance training associated with partial blood flow restriction: a randomized controlled clinical test

• Grant number: 19/17014-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Effective date (Start): February 01, 2020
• Effective date (End): February 28, 2021
• Field of knowledge: Biological Sciences - Physiology - Physiology of Effort
• Principal Investigator: Franciele Marques Vanderlei
• Grantee: Igor Martins da Silva
• Host Institution: Faculdade de Ciências e Tecnologia (FCT). Universidade Estadual Paulista (UNESP). Campus de Presidente Prudente. Presidente Prudente , SP, Brazil

Abstract

Studies show that resistance training (RT) programs related to partial blood flow restriction (RFS) are capable of promoting physical and functional gains such as increased muscle strength and hypertrophy. However, the autonomic and cellular effects of RFS associated with low-intensity resistance exercise are unknown. Tools such as heart rate variability (HRV) and bioelectrical impedance (IAB) may be useful in evaluating these outcomes and in better prescribing this alternative method of RT. Objective: To investigate and correlate the autonomic and vector responses of the low-intensity eccentric RT associated with the RFS. Method: This is a randomized controlled trial including 45 healthy men, aged 18 to 35 years, divided into two groups, with different intensities: 40% without RFS, 40% without RFS and 80% without RFS. Exercise intensity will be determined by the eccentric torque peak assessed by the isokinetic dynamometer and the RFS will be determined as 40% of the pressure required for complete RFS being assessed by Doppler. Participants will undergo a program of eccentric quadriceps muscle training on the isokinetic dynamometer at previously randomized intensity, lasting six weeks and three times weekly. RR interval and BIA evaluations will be performed at the 1st, 10th, and 18th training sessions, and RR interval collections will be performed at baseline for 15 minutes and at post-exercise recovery for 60 minutes immediately after the session ends. in which the rMSSD, HF [ms2 and nu] and SD1 vagal indices will subsequently be analyzed. The analysis of the IAB will take place before the TR and after the end of the recovery period after exercise and a global and segmental evaluation will be performed, and the resistance, reactance and phase angle (phA) will be analyzed. The descriptive statistical method will be used. The comparison of vagal indices and IAB vectors between the moments and groups will be performed by means of ANOVA for repeated measures model in the two-factor scheme followed by post hoc tests. The correlation will be used Pearson or Spearman test. The significance level will be p <0.05. (AU)