Study of the impact of gastrointestinal nematodes infection on the performance of Morada Nova Lambs for development of a targeted selective treatment

• Grant number: 18/16070-1
• Support Opportunities: Scholarships in Brazil - Doctorate
• Effective date (Start): January 01, 2020
• Effective date (End): December 31, 2021
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
• Principal Investigator: Ana Carolina de Souza Chagas
• Grantee: Isabella Barbosa dos Santos
• Host Institution: Embrapa Pecuária Sudeste. Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA). Ministério da Agricultura, Pecuária e Abastecimento (Brasil). São Carlos , SP, Brazil

Abstract

Brazil has great diversity in livestock, and the sheep flocks are endowed with different regionalized breeds and crosses with exotic breeds, appropriately adapted, such as Texel, Ile de France, Suffolk and Dorper. Besides these, there are still the hair sheep breeds, like Santa Inês and Morada Nova, from the arid region of the northeast of Brazil. However, gastrointestinal nematodes (GIN) are a major threat to these production systems, especially Haemonchus contortus, the prevalent specie in Brazilian herds. Economic losses are high due to decreased productivity, expenses with anthelmintics, and mortality. Among brazilian breeds, the Morada Nova proves to be quite resistant to verminosis, even in the pre and postpartum periods. This breed also presents: rusticity, prolificacy, quality skin, sexual precocity, excellent maternal ability, lack of reproductive seasonality, and adaptation to the tropical climate. In view of these factors, the present project aims to adapt a method for sheep deworming through a targeted selective treatment (TST) approach, taking production parameters into account, such as the means of daily weight gain of the lambs (Happy FactorTM). This strategy seems to be more adequate than the FAMACHA© method, since Morada Nova lambs usually maintain high packed cell volumes even when highly infected. We intend to verify the possibility of detecting the most infected animals, optimizing their weight gain and reducing GIN contamination on the pasture, maintaining representative refugia (parasite population with no exposure to anthelmintics), minimizing the selection of resistance alleles. Thus, it is expected to make this information available to sheep producers in order to encourage the creation of the Morada Nova breed. (AU)

Scientific publications

(4)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

OKINO, CINTIA HIROMI; FRIZONI CAMINOTTO, LARA CRISTINA; IKEDA KAPRITCHKOFF, RAFAELA TAMI; MEO NICIURA, SIMONE CRISTINA; ESTEVES, SERGIO NOVITA; DOS SANTOS, ISABELLA BARBOSA; BARBOSA TOSCANO, JOAO HENRIQUE; OLIVEIRA, M. C. S.; CHAGAS, A. C. S.. Comparison of ovine beta-globin haplotype sequences and a new multiplex PCR for identification. Veterinary Parasitology, v. 300, DEC 2021. (19/02929-3, 18/16070-1, 17/00373-2)

OKINO, CINTIA HIROMI; MEO NICIURA, SIMONE CRISTINA; BARBOSA TOSCANO, JOAO HENRIQUE; ESTEVES, SERGIO NOVITA; DOS SANTOS, ISABELLA BARBOSA; VON HAEHLING, MAREI BORSCH; FIGUEIREDO, AMANDA; DE SENA OLIVEIRA, MARCIA CRISTINA; DE SOUZA CHAGAS, ANA CAROLINA. Ovine beta-globin gene: A new qPCR for rapid haplotype identification and association with susceptibility to Haemonchus contortus infection. Veterinary Parasitology, v. 294, JUN 2021. (19/02929-3, 18/16070-1, 17/00373-2)

ANA CAROLINA DE SOUZA CHAGAS; OSCAR TUPY; ISABELLA BARBOSA DOS SANTOS; SÉRGIO NOVITA ESTEVES. Impacto econômico de nematódeos gastrintestinais em ovinos Morada Nova no Brasil. Revista Brasileira de Parasitologia Veterinária, v. 31, n. 3, 2022-08-19. (19/02929-3, 18/16070-1)

YOUSMEL ALEMÁN GAINZA; ISABELLA BARBOSA DOS SANTOS; AMANDA FIGUEIREDO; LEONARDO APARECIDO LIMA DOS SANTOS; SÉRGIO NOVITA ESTEVES; WALDOMIRO BARIONI-JUNIOR; ALESSANDRO PELEGRINE MINHO; ANA CAROLINA DE SOUZA CHAGAS. Resistência anti-helmíntica de Haemonchus contortus em rebanhos ovinos no Brasil: concordância de métodos in vivo e in vitro (RESISTA-Test©). Revista Brasileira de Parasitologia Veterinária, v. 30, n. 2, 2021-05-03. (16/07132-8, 14/25821-0, 17/13249-8, 18/16070-1)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SANTOS, Isabella Barbosa dos. Study of the impact of gastrointestinal nematodes infection on the performance of morada nova lambs for development of a targeted selective treatment. 2021. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Faculdade de Ciências Agrárias e Veterinárias. Jaboticabal Jaboticabal.