Study of the impact of gastrointestinal nematodes infection on the performance of Morada Nova Lambs for development of a targeted selective treatment

• Grant number: 18/16070-1
• Support Opportunities: Scholarships in Brazil - Doctorate
• Start date: January 01, 2020
• End date: December 31, 2021
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Preventive Veterinary Medicine
• Principal Investigator: Ana Carolina de Souza Chagas
• Grantee: Isabella Barbosa dos Santos
• Host Institution: Embrapa Pecuária Sudeste. Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA). Ministério da Agricultura, Pecuária e Abastecimento (Brasil). São Carlos , SP, Brazil

Abstract

Brazil has great diversity in livestock, and the sheep flocks are endowed with different regionalized breeds and crosses with exotic breeds, appropriately adapted, such as Texel, Ile de France, Suffolk and Dorper. Besides these, there are still the hair sheep breeds, like Santa Inês and Morada Nova, from the arid region of the northeast of Brazil. However, gastrointestinal nematodes (GIN) are a major threat to these production systems, especially Haemonchus contortus, the prevalent specie in Brazilian herds. Economic losses are high due to decreased productivity, expenses with anthelmintics, and mortality. Among brazilian breeds, the Morada Nova proves to be quite resistant to verminosis, even in the pre and postpartum periods. This breed also presents: rusticity, prolificacy, quality skin, sexual precocity, excellent maternal ability, lack of reproductive seasonality, and adaptation to the tropical climate. In view of these factors, the present project aims to adapt a method for sheep deworming through a targeted selective treatment (TST) approach, taking production parameters into account, such as the means of daily weight gain of the lambs (Happy FactorTM). This strategy seems to be more adequate than the FAMACHA© method, since Morada Nova lambs usually maintain high packed cell volumes even when highly infected. We intend to verify the possibility of detecting the most infected animals, optimizing their weight gain and reducing GIN contamination on the pasture, maintaining representative refugia (parasite population with no exposure to anthelmintics), minimizing the selection of resistance alleles. Thus, it is expected to make this information available to sheep producers in order to encourage the creation of the Morada Nova breed. (AU)

Scientific publications

(9)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

YOUSMEL ALEMÁN GAINZA; ISABELLA BARBOSA DOS SANTOS; AMANDA FIGUEIREDO; LEONARDO APARECIDO LIMA DOS SANTOS; SÉRGIO NOVITA ESTEVES; WALDOMIRO BARIONI-JUNIOR; ALESSANDRO PELEGRINE MINHO; ANA CAROLINA DE SOUZA CHAGAS. Resistência anti-helmíntica de Haemonchus contortus em rebanhos ovinos no Brasil: concordância de métodos in vivo e in vitro (RESISTA-Test©). Revista Brasileira de Parasitologia Veterinária, v. 30, n. 2, 2021-05-03. (18/16070-1, 17/13249-8, 14/25821-0, 16/07132-8)

DE SOUZA CHAGAS, ANA CAROLINA; TUPY, OSCAR; DOS SANTOS, ISABELLA BARBOSA; ESTEVES, SERGIO NOVITA. Economic impact of gastrointestinal nematodes in Morada Nova sheep in Brazil. REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA, v. 31, n. 3, p. 10-pg., 2022-01-01. (19/02929-3, 21/02535-5, 18/16070-1)

FIGUEIREDO, AMANDA; ANHOLETO, LUIS ADRIANO; COLA, DIEGO FARIA; FANTATTO, RAFAELA REGINA; GAINZA, YOUSMEL ALEMAN; DOS SANTOS, ISABELLA BARBOSA; VICOZZI, GABRIEL PEDROSO; AVILA, DAIANA SILVA; FRACETO, LEONARDO FERNANDES; CHAGAS, ANA CAROLINA DE SOUZA. Acaricides containing zein nanoparticles: A tool for a lower impact control of the cattle tick Rhipicephalus microplus. Veterinary Parasitology, v. 318, p. 11-pg., 2023-04-11. (19/20185-1, 18/16070-1, 17/13249-8, 17/21004-5)

OKINO, CINTIA HIROMI; NICIURA, SIMONE CRISTINA MEO; GIARETTA, PAULA ROBERTA; MELITO, GLAUCIA ROBERTA; KAPRITCHKOFF, RAFAELA TAMI IKEDA; DOS SANTOS, ISABELLA BARBOSA; RECH, RAQUEL RUBIA; MINHO, ALESSANDRO PELEGRINE; ESTEVES, SERGIO NOVITA; CHAGAS, ANA CAROLINA DE SOUZA. Enhanced mucosal response in sheep harbouring beta(A) beta-globin against haemonchosis. PARASITE IMMUNOLOGY, v. N/A, p. 12-pg., 2023-07-03. (22/00776-8, 21/02535-5, 18/16070-1, 19/02929-3)

ANA CAROLINA DE SOUZA CHAGAS; OSCAR TUPY; ISABELLA BARBOSA DOS SANTOS; SÉRGIO NOVITA ESTEVES. Impacto econômico de nematódeos gastrintestinais em ovinos Morada Nova no Brasil. Revista Brasileira de Parasitologia Veterinária, v. 31, n. 3, 2022-08-19. (19/02929-3, 18/16070-1)

DOS SANTOS, ISABELLA BARBOSA; ANHOLETO, LUIS ADRIANO; DE SOUSA, GUSTAVO AVELAR; NUCCI, ALESSANDRA DA SILVA; GAINZA, YOUSMEL ALEMAN; FIGUEIREDO, AMANDA; LIMA DOS SANTOS, LEONARDO APARECIDO; MINHO, ALESSANDRO PELEGRINE; BARIONI-JUNIOR, WALDOMIRO; ESTEVES, SERGIO NOVITA; et al. Investigating the benefits of targeted selective treatment according to average daily weight gain against gastrointestinal nematodes in Morada Nova lambs. Parasitology Research, v. N/A, p. 12-pg., 2022-05-28. (19/02929-3, 18/16070-1)

OKINO, CINTIA HIROMI; FRIZONI CAMINOTTO, LARA CRISTINA; IKEDA KAPRITCHKOFF, RAFAELA TAMI; MEO NICIURA, SIMONE CRISTINA; ESTEVES, SERGIO NOVITA; DOS SANTOS, ISABELLA BARBOSA; BARBOSA TOSCANO, JOAO HENRIQUE; OLIVEIRA, M. C. S.; CHAGAS, A. C. S.. Comparison of ovine beta-globin haplotype sequences and a new multiplex PCR for identification. Veterinary Parasitology, v. 300, DEC 2021. (19/02929-3, 18/16070-1, 17/00373-2)

OKINO, CINTIA HIROMI; MEO NICIURA, SIMONE CRISTINA; BARBOSA TOSCANO, JOAO HENRIQUE; ESTEVES, SERGIO NOVITA; DOS SANTOS, ISABELLA BARBOSA; VON HAEHLING, MAREI BORSCH; FIGUEIREDO, AMANDA; DE SENA OLIVEIRA, MARCIA CRISTINA; DE SOUZA CHAGAS, ANA CAROLINA. Ovine beta-globin gene: A new qPCR for rapid haplotype identification and association with susceptibility to Haemonchus contortus infection. Veterinary Parasitology, v. 294, JUN 2021. (19/02929-3, 18/16070-1, 17/00373-2)

SANTOS, ISABELLA B.; FERREIRA, AVELARDO U. C.; RABELO, MARCIO D.; ANHOLETO, LUIS ADRIANO; SOUSA, GUSTAVO A.; GAINZA, YOUSMEL A.; FIGUEIREDO, AMANDA; ESTEVES, SERGIO N.; CHAGAS, ANA CAROLINA S.. Portable near-infrared spectroscopy: A rapid and accurate blood test for diagnosis of Haemonchus contortus infection and for targeted selective treatment of sheep. International Journal for Parasitology, v. 53, n. 2, p. 9-pg., 2023-02-17. (17/13249-8, 16/07132-8, 18/16070-1, 19/02929-3)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SANTOS, Isabella Barbosa dos. Study of the impact of gastrointestinal nematodes infection on the performance of morada nova lambs for development of a targeted selective treatment. 2021. Doctoral Thesis - Universidade Estadual Paulista (Unesp). Faculdade de Ciências Agrárias e Veterinárias. Jaboticabal Jaboticabal.