Study of inhibitory and antitumor activity of natural substance-associated MAPK and WNT inhibitors in in vitro models

• Grant number: 19/25247-5
• Support Opportunities: Scholarships in Brazil - Technical Training Program - Technical Training
• Start date: February 01, 2020
• End date: July 31, 2021
• Field of knowledge: Health Sciences - Medicine - Medical Clinics
• Principal Investigator: Sara Teresinha Olalla Saad
• Grantee: Maura Lima Pereira Bueno
• Host Institution: Centro de Hematologia e Hemoterapia (HEMOCENTRO). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
• Associated research grant: 17/21801-2 - Predictors of severity and new treatments for bone marrow neoplasias, AP.TEM

Scientific publications

(5)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

BUENO, MAURA LIMA PEREIRA; SAAD, SARA TERESINHA OLALLA; ROVERSI, FERNANDA MARCONI. WNT5A in tumor development and progression: A comprehensive review. BIOMEDICINE & PHARMACOTHERAPY, v. 155, p. 18-pg., 2022-10-18. (19/25247-5, 17/21801-2, 21/05320-0)

BUENO, M. L. P.; FOGLIO, M.; SAAD, S. T. O.; ROVERSI, F. MARCONI. Tocotrienol exerts on-target malignant activity against leukemia. MOLECULAR BIOLOGY OF THE CELL, v. 34, n. 2, p. 2-pg., 2023-02-01. (17/21801-2, 21/05320-0, 19/25247-5)

PEREIRA BUENO, MAURA LIMA; ARTICO, LEONARDO; SANTOS DUARTE, ADRIANA SILVA; BASSO, AUDREY; YUNES, JOSE ANDRES; SAAD, SARA T. OLALLA; ROVERSI, FERNANDA MARCONI. Combined Inhibition of MCL1 By AZD5991 and BCL2/Bclxl By AZD4320 As Promising Strategies to Overcome Acute Leukemia Tumor Burden and Niche Chemoresistance. Blood, v. 140, p. 2-pg., 2022-11-15. (17/21801-2, 21/05320-0, 19/25247-5)

ROVERSI, FERNANDA MARCONI; PEREIRA BUENO, MAURA LIMA; BASSO, AUDREY; SANTOS DUARTE, ADRIANA SILVA; SILVA, JULIETE A. F.; OLALLA SAAD, SARA T.. HCK Inhibition Displays Antineoplastic Activity on Acute Leukemia and Promotes Immune Regulation of the Bone Marrow Tumor Microenvironment. Blood, v. 140, p. 2-pg., 2022-11-15. (17/21801-2, 21/05320-0, 19/25247-5)

ROVERSI, FERNANDA MARCONI; PEREIRA BUENO, MAURA LIMA; FRANCISCO DA SILVA, JULIETE APARECIDA; ASSIS-MENDONCA, GUILHERME ROSSI; OLALLA SAAD, SARA TERESINHA. Optimized multiplex immunofluorescence for the characterization of tumor immune microenvironment in neoplastic paraffin-preserved tissues. JOURNAL OF CELL COMMUNICATION AND SIGNALING, v. 17, n. 3, p. 11-pg., 2023-05-16. (17/21801-2, 21/05320-0, 19/25247-5)