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Evaluation of root fractures in different CBCT devices using different parameters and detections of dentinal microcracks by nano-CT

Grant number: 19/22885-0
Support Opportunities:Scholarships abroad - Research Internship - Doctorate
Effective date (Start): August 01, 2020
Effective date (End): July 31, 2021
Field of knowledge:Health Sciences - Dentistry - Endodontics
Principal Investigator:Mario Tanomaru Filho
Grantee:Jáder Camilo Pinto
Supervisor: Reinhilde Jacobs
Host Institution: Faculdade de Odontologia (FOAr). Universidade Estadual Paulista (UNESP). Campus de Araraquara. Araraquara , SP, Brazil
Research place: University of Leuven, Leuven (KU Leuven), Belgium  
Associated to the scholarship:18/19665-6 - Effect of the acquisition and analysis of the images in micro-CT in the evaluation of different phases of endodontic treatment in mandibular molars, BP.DR


Subproject 1: This study aims to assess root fractures/cracks in CBCT images with and without metalstructures within and outside of the field of view using different devices. An anthropomorphicphantom covered with Mix-D material simulating soft tissue will be manufactured. Three sets willrepresent different clinical conditions: 1. Control group - human mandible free of metal andcontaining fractures/cracks in several teeth; 2. Metallic group - human mandible containing a premolarwith endodontic treatment and intracanal metallic post in its contralateral pre-molar, and severalteeth containing fractures/cracks; 3. Implant group - human mandible with titanium implants andzirconium abutments placed in the region of pre-molars and containing fractures/cracks in severalteeth. For the reference image acquisition, the phantom will be scanned by using an industrial micro-CT device (Nikon XTH 450 Industrial x-ray). For CBCT analysis, the images will be acquired in 12commercial devices selecting 3 different clinical comparable protocols defined for each machine.Image registration will be performed using Amira software, and the analysis will be performed by 3Dentomaxillofacial Radiologists. A visual grading characteristics analysis (VGC) / Forced Choicemethod for diagnostic will be used. The ability to detect root fractures in twelve different CBCTdevices in different simulated clinical situations will be evaluated. Subproject 2: Aims to evaluatethe presence of dentinal microcracks by using nano-CT. Mandibular incisors with a single straight rootcanals and lateral apical foramen will be select after micro-CT scanning at 35 micrometers resolution. Nano-CT scanning at 3 micrometers of voxel size will be performed before preparation for total sample (control group/ n=16) and after the two root canal preparation techniques (n = 8 for each group). The root canals willbe prepared by Reciproc Blue R 40 1 mm short of apical foramen or 1 mm beyond the apical foramen.The presence of microcracks will be evaluated in the apical third (4mm) after image registration(before and after) using Amira software. All stages of this project will be performed in a partnershipproposed with the School of Medicine, KU Leuven, Belgium. The results obtained will be submittedto the proper statistical test. (AU)

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Scientific publications (7)
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
JÁDER CAMILO PINTO; HERNÁN COAGUILA-LLERENA; FERNANDA FERRARI ESTEVES TORRES; ÉVERTON LUCAS-OLIVEIRA; TITO JOSÉ BONAGAMBA; JULIANE MARIA GUERREIRO-TANOMARU; MÁRIO TANOMARU-FILHO. Influence of voxel size on dentinal microcrack detection by micro-CT after root canal preparation. Brazilian Oral Research, v. 35, . (19/22885-0, 17/19049-0, 18/19665-6)
PINTO, JADER CAMILO; WANDERLEY, VICTOR AQUINO; VASCONCELOS, KARLA DE FARIA; LEITE, ANDRE FERREIRA; PAUWELS, RUBEN; NADJMI, MANSOUR; OLIVEIRA, MATHEUS L.; TANOMARU-FILHO, MARIO; JACOBS, REINHILDE. Evaluation of 10 Cone-beam Computed Tomographic Devices for Endodontic Assessment of Fine Anatomic Structures. JOURNAL OF ENDODONTICS, v. 47, n. 6, p. 947-953, . (19/22885-0)
PINTO, JADER CAMILO; COAGUILA-LLERENA, HERNAN; ESTEVES TORRES, FERNANDA FERRARI; LUCAS-OLIVEIRA, EVERTON; BONAGAMBA, TITO JOSE; GUERREIRO-TANOMARU, JULIANE MARIA; TANOMARU-FILHO, MARIO. Influence of voxel size on dentinal microcrack detection by micro-CT after root canal preparation. BRAZILIAN ORAL RESEARCH, v. 35, p. 8-pg., . (18/19665-6, 19/22885-0)
SANTOS-JUNIOR, AIRTON OLIVEIRA; TANOMARU-FILHO, MARIO; PINTO, JADER CAMILO; MEDINA CARITA TAVARES, KARINA INES; ESTEVES TORRES, FERNANDA FERRARI; GUERREIRO-TANOMARU, JULIANE MARIA. Effect of obturation technique using a new bioceramic sealer on the presence of voids in flattened root canals. BRAZILIAN ORAL RESEARCH, v. 35, p. 9-pg., . (17/14305-9, 19/22885-0, 17/19049-0, 16/00321-0)
AIRTON OLIVEIRA SANTOS-JUNIOR; MÁRIO TANOMARU-FILHO; JÁDER CAMILO PINTO; KARINA INES MEDINA CARITA TAVARES; FERNANDA FERRARI ESTEVES TORRES; JULIANE MARIA GUERREIRO-TANOMARU. Effect of obturation technique using a new bioceramic sealer on the presence of voids in flattened root canals. Brazilian Oral Research, v. 35, . (17/19049-0, 19/22885-0, 16/00321-0, 17/14305-9)
PINTO, JADER CAMILO; VASCONCELOS, KARLA DE FARIA; LEITE, ANDRE FERREIRA; WANDERLEY, VICTOR AQUINO; PAUWELS, RUBEN; OLIVEIRA, MATHEUS L.; JACOBS, REINHILDE; TANOMARU-FILHO, MARIO. Image quality for visualization of cracks and fine endodontic structures using 10 CBCT devices with various scanning protocols and artefact conditions. SCIENTIFIC REPORTS, v. 13, n. 1, p. 10-pg., . (19/22885-0)
PINTO, JADER CAMILO; DE FARIA-VASCONCELOS, KARLA; LEITE, ANDRE FERREIRA; PEDANO, MARIANO SIMON; GUERREIRO-TANOMARU, JULIANE; JACOBS, REINHILDE; TANOMARU-FILHO, MARIO. Effect of foraminal enlargement on microcrack formation and apical transportation: a nano-CT assessment. SCIENTIFIC REPORTS, v. 13, n. 1, p. 7-pg., . (19/22885-0)

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