Effect of time delay and plasticity in neuronal synchronization

• Grant number: 19/09150-1
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: July 01, 2020
• End date: June 30, 2022
• Field of knowledge: Engineering - Electrical Engineering - Industrial Electronics, Electronic Systems and Controls
• Principal Investigator: Elbert Einstein Nehrer Macau
• Grantee: Matheus Hansen Francisco
• Host Institution: Instituto de Ciência e Tecnologia (ICT). Universidade Federal de São Paulo (UNIFESP). Campus São José dos Campos. São José dos Campos , SP, Brazil
• Associated research grant: 15/50122-0 - Dynamic phenomena in complex networks: basics and applications, AP.TEM

Abstract

In this project, we investigate the behavior of a neuronal network with dynamics described by the Hodgkin and Huxley model, with interest in investigating the synchronization of neuronal activities through newly developed numerical diagnoses. The Neuronal synchronization has attracting attention of the scientific community, because this type of behavior is associated with known brain pathologies, such as Epilepsy and Parkinson's Disease. Given this scenario, we investigated a network with random initial architecture, considering the existence of excitatory (inhibitory) chemical synapses, as well as the presence of plasticity and the time delay in neuronal connections. The Plasticity is linked to the ability to transmit information among neurons, and the time delay represents a delay in conducting this information. In this context, we simulate the effect of plasticity by introducing synaptic weights into the system, and the time delay is represented by a control parameter to be inserted in the dynamics discussed. At the end of this proposal, we will have characterized the behavior of synchronization (desynchronization) of the network, besides to classifying possible complex structures in the parameter spaces of the model. (AU)

Scientific publications

(6)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DA COSTA, DIOGO RICARDO; HANSEN, MATHEUS; SILVA, MARIO ROBERTO; LEONEL, EDSON D.. Tangent Method and Some Dynamical Properties of an Oval-Like Billiard. INTERNATIONAL JOURNAL OF BIFURCATION AND CHAOS, v. 32, n. 04, p. 15-pg., 2022-03-30. (19/14038-6, 20/02415-7, 19/09150-1)

PROTACHEVICZ, PAULO R.; HANSEN, MATHEUS; IAROSZ, KELLY C.; CALDAS, IBERE L.; BATISTA, ANTONIO M.; KURTHS, JURGEN. Emergence of Neuronal Synchronisation in Coupled Areas. FRONTIERS IN COMPUTATIONAL NEUROSCIENCE, v. 15, APR 22 2021. (19/09150-1, 20/04624-2, 15/50122-0, 18/03211-6)

HANSEN, MATHEUS; PROTACHEVICZ, PAULO R.; IAROSZ, KELLY C.; CALDAS, IBERE L.; BATISTA, ANTONIO; MACAU, ELBERT E. N.. Dynamics of uncoupled and coupled neurons under an external pulsed current. CHAOS SOLITONS & FRACTALS, v. 155, p. 10-pg., 2022-02-01. (18/03211-6, 20/04624-2, 19/09150-1, 15/50122-0)

HANSEN, MATHEUS; LANES, GABRIEL C.; BRITO, VINICIUS L. G.; LEONEL, EDSON D.. Investigation of pollen release by poricidal anthers using mathematical billiards. Physical Review E, v. 104, n. 3, SEP 13 2021. (19/14038-6, 19/09150-1)

SAYARI, ELAHEH; BATISTA, ANTONIO M.; GABRICK, ENRIQUE C.; IAROSZ, KELLY C.; HANSEN, MATHEUS; SZEZECH, JOSE D., JR.; BORGES, FERNANDO S.. Dynamics of a perturbed random neuronal network with burst-timing-dependent plasticity. European Physical Journal-Special Topics, v. 231, n. 22-23, p. 8-pg., 2022-10-17. (19/09150-1)

HANSEN, MATHEUS; PROTACHEVICZ, PAULO R.; IAROSZ, KELLY C.; CALDAS, IBERE L.; BATISTA, ANTONIO M.; MACAU, ELBERT E. N.. The effect of time delay for synchronisation suppression in neuronal networks. CHAOS SOLITONS & FRACTALS, v. 164, p. 10-pg., 2022-11-01. (18/03211-6, 20/04624-2, 19/09150-1, 15/50122-0)