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Chemical study of the Caatinga propolis produced by Apis mellifera and re-isolation of red propolis compounds to perform biological tests and develop analytical methods.

Grant number: 21/01411-0
Support type:Scholarships in Brazil - Post-Doctorate
Effective date (Start): August 01, 2021
Effective date (End): January 31, 2023
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Organic Chemistry
Principal researcher:Jairo Kenupp Bastos
Grantee:Ninh The Son
Home Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
Associated research grant:17/04138-8 - Attainment of chemical, analytical, biological, pharmacological and technological studies to fill the gaps on the development of Brazilian propolis sector, AP.TEM

Abstract

Brazilian propolis produced by Apis mellifera, popularly known as green, brown, and red, with approximately 200 tons produced per year, is highly economically relevant to Brazil since they are exported to several countries, especially Japan and China. In addition to the well-known propolis, there is propolis that has not yet been studied, as is the case of propolis produced in Northeastern Brazil's "Caatinga vegetation." This propolis has market potential, but studies must be carried out to develop this new Brazilian propolis. Thus, it is proposed to carry out detailed chemical studies of isolation and structural identification of the major and minor metabolites of this unprecedented propolis from the Caatinga and its botanical source. Also, red propolis compounds, whose botanical sources are Dalbergia ecastaphyllumm and Symphonia globulifera, will be re-isolated to be used in the development of analytical methods and conducting biological tests in the ongoing thematic project entitled: "Conducting chemical, analytical, biological, pharmacological and technological studies to fill the gaps in the development of the Brazilian propolis sector." (AU)

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