Assessment of depression, stress and anxiety (DASS-21) and the impact of oral health on quality of life (OHIP-14) in individuals with Sjogren's Syndrome

• Grant number: 20/15698-7
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: May 01, 2021
• End date: December 31, 2021
• Field of knowledge: Health Sciences - Dentistry
• Principal Investigator: Paulo Sérgio da Silva Santos
• Grantee: Raquel Machado Gabia
• Host Institution: Faculdade de Odontologia de Bauru (FOB). Universidade de São Paulo (USP). Bauru , SP, Brazil

Abstract

Sjögren's syndrome (SS) is a chronic autoimmune inflammatory systemic disease, characterized by the infiltration of mononuclear cells in exocrine glands, leading to physiological and morphological changes due to the destruction of the cells that make up the structures. In the literature, few studies report on the physical, social, and psychological well-being of these individuals. The present prospective clinical study aims to describe the profile, evaluate the oral condition and the impact on the quality of life (QOL) and psychological condition, through a complete clinical examination, OHIP-14, and DASS-21 questionnaires, respectively, in individuals with SS to relate to the evolution of the disease. Patients diagnosed with Sjogren's Syndrome, from December / 1974 to November / 2018, attended the Stomatology Clinic of the Faculty of Dentistry of Bauru, University of São Paulo (FOB-USP), will be recruited at the time of the follow-up consultation. a routine at the Stomatology Graduate Clinic, to reevaluate signs and symptoms and perform a new clinical examination and given the current diagnosis, establish oral care protocols. Individuals aged up to 70 years and with updated telephone contact will be included. At this point, the first questionnaire (OHIP-14) will be applied, which will assess the impact of oral health on the patient's quality of life, where seven dimensions are evaluated, subdivided into 14 questions using the Lickert scale (0 to 4) assigned by the individual and that quantifies the impact of oral health on QOL. The second questionnaire (DASS-21), will assess the patient's psychological condition, which presents seven questions for each emotional state (depression, anxiety, and stress), totaling many 21 questions. Later, it is expected to relate the clinical condition, the evolution of SS, oral clinical condition, and the profile of this population to the QoL factors and psychological conditions, using these assessment instruments.