Scholarship 21/14732-0 - Grafenos, Dispositivos eletroquímicos - BV FAPESP
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Development of electrochemical devices based on graphene obtained by advanced inkjet-printing and laser-scribing techniques as platforms to monitor biomarkers

Grant number: 21/14732-0
Support Opportunities:Scholarships abroad - Research Internship - Post-doctor
Start date until: April 01, 2022
End date until: March 31, 2023
Field of knowledge:Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
Principal Investigator:Lauro Tatsuo Kubota
Grantee:Patrícia Batista Deroco
Supervisor: Arben Merkoci
Host Institution: Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil
Institution abroad: Catalan Institute of Nanoscience and Nanotechnology (ICN2), Spain  
Associated to the scholarship:19/00166-2 - Paper-Based Electrochemical Biosensor for Traumatic Brain Injury detection, BP.PD

Abstract

The COVID-19 outbreak showed us the need for improvement and new, simpler and more practical diagnostic technologies. In this sense, the combination of advanced materials such as graphene and its derivatives with automated techniques for obtaining electrodes, as well as inkjet printing and laser-scribing, can generate devices without the need for additional modifications to the printed electrochemical sensors. This is because graphene provides highly conductive and flexible films and its functional groups facilitate direct covalent binding with bioreceptor via carbodiimide coupling. However, one of the main challenges of printing with pure graphene is the tendency of the material to aggregate, once it is difficult to disperse it in liquids with the necessary properties for inkjet printing. This leads to the development of new inkjet ink formulations and the application of new technologies to obtain more practical, cheaper and easier-to-use graphene-based electrodes, mainly aiming to break the academic research barrier to make such devices marketable. Thus, this project aims to development of new formulation of graphene-based ink and to apply advanced and automated inkjet printing and laser scribing technologies in the fabrication of a platform to employ in high-sensitivity electrochemical biosensors. The immobilization of biological materials on the sensor surface will allow the development of a biosensor for monitoring the microbiome, as a novel diagnostic strategy for customized medicine. (AU)

News published in Agência FAPESP Newsletter about the scholarship:
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Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
DEROCO, PATRICIA BATISTA; WACHHOLZ JUNIOR, DAGWIN; KUBOTA, LAURO TATSUO. Paper-based Wearable Electrochemical Sensors: a New Generation of Analytical Devices. Electroanalysis, v. N/A, p. 12-pg., . (21/14732-0, 14/50867-3, 13/22127-2, 19/00166-2, 21/09706-0)

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