Development and evaluation of the effectiveness of cosmetic formulations for tattooed skin care

• Grant number: 21/10186-0
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: February 01, 2022
• End date: March 31, 2023
• Field of knowledge: Health Sciences - Pharmacy - Pharmaceutical Technology
• Principal Investigator: Patrícia Maria Berardo Gonçalves Maia Campos
• Grantee: Laura Noronha Favaro
• Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated scholarship(s): 22/05122-6 - Evaluation of the mechanism of action of topic formulations with moisturizing and antioxidant properties, BE.EP.IC

Abstract

The use of cosmetics is intimately connected with the quality of life, well-being, and consumer self-esteem. This way, the development of cosmetics with proven efficacy for all skin types, including tattooed skin, is fundamental to attend to the demand for increasingly innovative products. Considering the 20% per year growth of this market, it is possible to infer that tattooing skin has become more popular in Brazil. Tattooing involves the process of repeatedly inserting pigments into the dermis through a machine that can pierce the skin up to three thousand times per minute, causing tissue damage. Furthermore, the most exposed regions to solar radiation are even more affected, which could lead to color fading. Therefore, the tattooed skin needs specific care to maintain the well-defined characteristics and color of the tattoo for a longer period of time. However, it is notable the scarcity of studies about cosmetics development and evaluation to the care of tattooed skin. Formulations for tattooed skin must have protective, moisturizing, and repairing effects, therefore, the addition of D-panthenol, which is moisturizing, protective, and repairing the skin's barrier function and anti-inflammatory, in cosmetic formulations can improve the protection and care for this skin type. In this context, this project aims to characterize tattooed skin, develop minimalist cosmetic formulations added to D-panthenol, and evaluate the clinical efficiency in the long term using biophysical and skin imaging techniques. Finally, this study contributes to the development of cosmetics products specific to tattooed skin, attending to the market demand. (AU)