Production and analysis of scaffolds of alumina-zirconia nanocomposites (SNA-Z)

• Grant number: 22/00583-5
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: June 01, 2022
• End date: May 31, 2023
• Field of knowledge: Agronomical Sciences - Veterinary Medicine - Animal Clinics and Surgery
• Principal Investigator: Silvio Henrique de Freitas
• Grantee: Julia Merilis Silva
• Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil

Abstract

The orthopedic disorders that require repairing surgical treatment with the use of bone substitutes are frequent not only in human medicine but also in veterinary medicine. The aim of this research is to produce scaffolds of alumina-zirconia nanocomposites (SNA-Z) coated with calcium phosphate for seven days (7d) and submit them to an analysis by scanning electron microscopy (SEM), stereomicroscope, and cytotoxicity assay. It is expected as a result that SNA-Z(7d) has the potential for clinical application and can be used as an alternative in the repair of orthopedic injuries with great bone loss, with satisfactory results, low cost, easy acquisition, and access to improving the quality of life of not only human patients but also veterinarians.(AU)