Head circumference trajectories in early childhood in Cruzeiro do Sul, Acre: associated factors and relationship with child development

• Grant number: 22/03400-9
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• Start date: August 01, 2022
• End date: July 31, 2025
• Field of knowledge: Health Sciences - Nutrition - Nutritional Analysis of Population
• Principal Investigator: Marly Augusto Cardoso
• Grantee: Isabel Giacomini Marques
• Host Institution: Faculdade de Saúde Pública (FSP). Universidade de São Paulo (USP). São Paulo , SP, Brazil
• Associated research grant: 16/00270-6 - MINA study - Maternal and child health in Acre: birth cohort in the Western Brazilian Amazon, AP.TEM
• Associated scholarship(s): 23/15198-2 - Social inequalities and behavioural difficulties in childhood across cohort studies, BE.EP.DD

Abstract

There are few longitudinal studies on child development in low- and middle-income countries. The present study aims to investigate determinants of health and nutritional status in early life and their relationship with child development and behavioral disorders in preschool children in the MINA-Brazil birth cohort. Between July 2015 and June 2016, mothers and babies were recruited from the only maternity hospital in the municipality of Cruzeiro do Sul, Acre, Western Brazilian Amazon. With 1246 eligible mother-infant pairs at baseline, participants were followed at 6-8 months, 1, 2, and 5 years of age. The central hypothesis of this project is that intergenerational and perinatal factors are associated with head growth up to 2 years of age, impacting child development and behavioral disorders at 5 years of age. This project includes five main objectives: I) to systematically review the role of breastfeeding and head circumference in the first two years of life (article 1); II) to assess the internal consistency of the scales of the parents' version of the Abilities and Difficulties Questionnaire (SDQ-P) in our study population (article 2); III) investigate factors associated with behavioral disorders in preschoolers in the context of the COVID-19 pandemic (article 3); IV) investigate the relationship between nutritional status and child development at two years of age (article 4); V) investigate head circumference growth trajectories and their association with child development and behavior at preschool age (article 5). The results will contribute to the definition of policy priorities to promote adequate child development, aiming at reducing inequalities in contexts of social vulnerability. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

ALICIA MATIJASEVICH; ALEXANDRE FAISAL-CURY; ISABEL GIACOMINI; JULIA DE SOUZA RODRIGUES; MARCIA C. CASTRO; MARLY A. CARDOSO. Depressão materna e saúde mental infantil aos cinco anos de idade: Estudo de coorte MINA-Brasil. Revista de Saúde Pública, v. 57, 2024-02-26. (16/00270-6, 21/01688-2, 22/03400-9, 20/13425-3)

ISABEL GIACOMINI; MARIA ROSÁRIO O. MARTINS; ALICIA MATIJASEVICH; MARLY A. CARDOSO. Consistência interna do Questionário de Capacidades e Dificuldades em crianças amazônicas. Revista de Saúde Pública, v. 57, 2024-02-26. (16/00270-6, 21/01688-2, 22/03400-9)

GIACOMINI, ISABEL; VILLAMOR, EDUARDO; LOURENCO, BARBARA HATZLHOFFER; ZHU, MIA; SEELEY, ALLISON L.; MATIJASEVICH, ALICIA; CARDOSO, MARLY AUGUSTO. Impaired head circumference growth and behavioural problems in childhood: Longitudinal findings from the MINA-Brazil birth cohort. Paediatric and Perinatal Epidemiology, v. N/A, p. 11-pg., 2024-10-04. (22/03400-9, 21/01688-2, 16/00270-6)