Large-scale data integration to study gene expression dynamics of Aspergillus fumigatus metabolic pathways related to caspofungin's antifungal action

• Grant number: 22/13603-4
• Support Opportunities: Scholarships in Brazil - Technical Training Program - Technical Training
• Start date: November 01, 2022
• End date: May 31, 2023
• Field of knowledge: Biological Sciences - Microbiology - Biology and Physiology of Microorganisms
• Principal Investigator: Gustavo Henrique Goldman
• Grantee: Endrews Delbaje
• Host Institution: Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP). Universidade de São Paulo (USP). Ribeirão Preto , SP, Brazil
• Associated research grant: 21/04977-5 - The identification of new pathways and compounds that can enhance caspofungin activity against Aspergillus fumigatus, AP.TEM

Abstract

Azoles são drogas fungicidas para A. fumigatus e os principais agentes antifúngicos recomendados para o tratamento de Aspergilose pulmonar invasiva (IPA). As equinocandinas, tais como caspofungin (CSP), representam uma segunda linha de terapia e tem como

Scientific publications

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

PINZAN, CAMILA FIGUEIREDO; VALERO, CLARA; DE CASTRO, PATRICIA ALVES; DA SILVA, JEFFERSON LUIZ; EARLE, KAYLEIGH; LIU, HONG; HORTA, MARIA AUGUSTA CRIVELENTE; KNIEMEYER, OLAF; KRUGER, THOMAS; PSCHIBUL, ANNICA; et al. Aspergillus fumigatus conidial surface-associated proteome reveals factors for fungal evasion and host immunity modulation. NATURE MICROBIOLOGY, v. 9, n. 10, p. 30-pg., 2024-08-27. (22/13603-4, 22/08796-8, 20/04923-0, 18/18257-1, 18/15549-1, 21/04977-5)

OUYANG, XIAODAN; WAHLSTEN, MATTI; POLLARI, MAIJA; DELBAJE, ENDREWS; JOKELA, JOUNI; FEWER, DAVID P.. Identification of a homoarginine biosynthetic gene from a microcystin biosynthetic pathway in Fischerella sp. PCC 9339. Toxicon, v. 243, p. 10-pg., 2024-05-03. (22/13603-4)

DIEHL, CAMILA; PINZAN, CAMILA FIGUEIREDO; DE CASTRO, PATRICIA ALVES; DELBAJE, ENDREWS; CARNERO, LAURA C. GARCIA; SANCHEZ-LEON, EDDY; BHALLA, KABIR; KRONSTAD, JAMES W.; KIM, DONG-GYU; DOERING, TAMARA L.; et al. Brilacidin, a novel antifungal agent against Cryptococcus neoformans. MBIO, v. 15, n. 7, p. 28-pg., 2024-06-25. (22/13603-4, 22/08796-8, 21/10599-3, 21/04977-5)