Determination of a green synthesis method to obtain silver nanoparticles containing Euterpe edulis Mart. based food supplement (AnthocyanOx®): evaluation of the antiglycant and antioxidant activity

• Grant number: 23/04247-2
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: November 01, 2023
• End date: July 31, 2025
• Field of knowledge: Biological Sciences - Biology
• Principal Investigator: Regildo Márcio Gonçalves da Silva
• Grantee: Monique Maria de Oliveira Costa
• Host Institution: Faculdade de Ciências e Letras (FCL-ASSIS). Universidade Estadual Paulista (UNESP). Campus de Assis. Assis , SP, Brazil
• Associated scholarship(s): 24/08165-3 - Biohybrid nanoparticles for the adsorption and release of anthocyanins, BE.EP.IC

Abstract

The food supplement based on Euterpe edulis Mart., AnthocyanOx®, is a product of vegetable origin developed by Atina - Ativos Naturais (Pouso Alegre - MG), a standardized extract with the anthocyanins present in the fruit of E. edulis palm tree, popularly known as palmito-juçara or juçara, which grows only in the Atlantic Forest located in the coastal region of Brazil and can be cultivated for exploitation of edible palm heart. The species E. edulis is known to have an antioxidant concentration five times higher than Euterpe oleracea Mart (Açai), a palm tree endemic to the Amazon rainforest and known in Brazil as a "superfood". Considering the antioxidant and marketing potential of the product AnthocyanOx®, this work aims to develop a method to obtain silver nanoparticles containing food supplement based on E. edulis (AnthocyanOx®), through the green synthesis nanotechnology. It also aims to characterize the nanoparticles and evaluate the antioxidant activity through in vitro tests of free radical scavenging DPPH, of the Fe+3 ion (FRAP), of the ABTS radical and lipid peroxidation (TBARS), as well as the antiglycation activity, by the method of protein mobility in electrophoresis and determination of free amino group. It will also determine the content of phenols, flavonoids and total anthocyanins in silver nanoparticles containing E. edulis-based food supplement.

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

DOS SANTOS, VALTER HENRIQUE MARINHO; COSTA, MONIQUE MARIA DE OLIVEIRA; GRANERO, FILIPE OLIVEIRA; FIGUEIREDO, CELIA CRISTINA MALAGUTI; SANTOS, HUGO HENRIQUE; BENEVIDES, PAULO JOSE COELHO; NICOLAU-JUNIOR, NILSON; DEBIAGI, PAULO EDUARDO AMARAL; SILVA, LUCIANA PEREIRA; DA SILVA, REGILDO MARCIO GONCALVES. Green biosynthesis of silver nanoparticles using anthocyanins-rich extract from Euterpe edulis fruits (AnthocyanOx®): Assessment in vitro of antioxidant and antiglycation activities, and in silico anti-aging activity. FOOD AND BIOPRODUCTS PROCESSING, v. 151, p. 13-pg., 2025-05-01. (23/04247-2)