Effect of dietary supplementation with different sources of organic and inorganic selenium on milk production and composition and on the oxidative profile of blood and milk in lactating Holstein cows.

• Grant number: 23/15975-9
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• Start date: July 01, 2024
• End date: October 31, 2025
• Field of knowledge: Agronomical Sciences - Animal Husbandry - Animal Nutrition and Feeding
• Principal Investigator: Arlindo Saran Netto
• Grantee: Ana Júlia Lacerda dos Santos
• Host Institution: Faculdade de Zootecnia e Engenharia de Alimentos (FZEA). Universidade de São Paulo (USP). Pirassununga , SP, Brazil
• Associated research grant: 21/07131-0 - Biofortification of milk with selenium: effect on nutritional bioavailability and action on human health, AP.TEM
• Associated scholarship(s): 24/18580-8 - Profiling of DHA, EPA, and arachidonic acid pro-resolving mediators in plasma samples of postpartum dairy cows suffering from different degrees of systemic inflammation, BE.EP.IC

Abstract

Selenium is a micronutrient that performs several important functions in the animal organism, mainly related to its antioxidant properties. This micronutrient has great potential to promote improvements in the health of the mammary gland of dairy cows and consequently benefits to milk production, which able to increase quality and milk production, when associated with adequate management and nutrition. The present study aims to analyze the effects of dietary supplementation with different sources of organic and inorganic selenium on the composition and production of milk and oxidative profile in blood and milk in lactating Holstein cows. The study will be conducted in the Dairy Cattle Sector of City Hall of Pirassununga of the University of São Paulo. 32 lactating Holstein cows with 120 ± 60 days in lactation (DEL) will be used, body weight of 700 ± 100 kg, average body condition score (BCS) of 3,0 ± 1,0 e milk production of 25,0 ± 5,0 kg milk/cow/day. The experimental design adopted will be in randomized blocks with repeated measurements over time, 100 days of duration, with the 14 first days being used to diet adaptation of the cows and the remainder for collecting data and samples. The treatments tested will be control diet; control diet + inorganic selenium (SE_In) (Sodium selenite); control diet + yeast selenium (SE_Lv) (SEL-PLEX ® Alltech); control diet + aminoacid selenium (SE_AA) ((SELISSEO ® Adisseo).