Application of analytical microsystems constructed with LTCC (Low temperature Co-fired ceramics) for glucose, cholesterol and urea determination by means of enzimatic reactions with chemiluminescence and spectrophotometric detection

• Grant number: 08/11151-1
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• Start date: April 01, 2009
• End date: August 31, 2010
• Field of knowledge: Physical Sciences and Mathematics - Chemistry - Analytical Chemistry
• Principal Investigator: Ana Rita de Araujo Nogueira
• Grantee: Willian Toito Suarez
• Host Institution: Embrapa Pecuária Sudeste. Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA). Ministério da Agricultura, Pecuária e Abastecimento (Brasil). São Carlos , SP, Brazil

Abstract

In this work, will be developed automatized procedures in flow with chemiluminescence or spectrophotometric detection employing analytical microsystems constructed with LTCC technology (Low Temperature Co-fired Ceramics), multicommutation and solid phase reactor. These procedures will be utilized to glucose determination in bovine blood serum and food samples, cholesterol in bovine and ovine meat, and urea in milk samples. With the automatization of the procedures and employing of the solid phase reactor, it is intended to minimize the manipulation of the samples, reduce the reagent consumption, and increase the sample frequency with higher measurement precision and increase of the sensitivity. With the miniaturization of the analytical system employing LTCC it is intended to integrate the fluidic and detection system at the same structure with the final goal of construct a micro total analyses system. (AU)

Scientific publications

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

SUAREZ, WILLIAN TOITO; PESSOA-NETO, OSMUNDO DANTAS; JANEGITZ, BRUNO CAMPOS; VIEIRA, HEBERTH JULIANO; FARIA, RONALDO CENSI; FATIBELLO-FILHO, ORLANDO. FLOW INJECTION SPECTROPHOTOMETRIC DETERMINATION OF N-ACETYLCYSTEINE AND CAPTOPRIL EMPLOYING PRUSSIAN BLUE GENERATION REACTION. Analytical Letters, v. 44, n. 14, p. 2394-2405, 2011. (08/09893-0, 08/11151-1)