Full text
| |
| Author(s): |
Pedro Paulo Menezes Scariot
Total Authors: 1
|
| Document type: | Master's Dissertation |
| Press: | Limeira, SP. |
| Institution: | Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas |
| Defense date: | 2014-12-05 |
| Examining board members: |
Claudio Alexandre Gobatto;
Gustavo Gomes de Araujo;
José Rodrigo Pauli
|
| Advisor: | Claudio Alexandre Gobatto |
| Abstract | |
Locomotion is extremely important and essential for animal life behavior. Thus, it becomes clear that the restricted confinement and therefore the suppression of many locomotors behaviors imposed to laboratory animals can cause negative physiological implications. Based on these problems, we verified if animals housed in conventional cages have worse exercise performance indicators when compared to animals exposed in increased housing space. Furthermore, we analyzed if the physical space of the cages is a more important factor than implementation of the exercise, given that physical training protocols in animal models fail to promote improvements in aerobic capacity over the age. On another topic, locomotion is closely related to genetic factors. We assumed that animals more active in the cage, exhibit higher metabolic and genetic advantages for the practice of exercise when compared to inactive animals. Therefore, we investigated whether the spontaneous and voluntary activities of animals already reflect propensities for better physical performance. Although they look similar, these activities are considered distinct in the literature. There is scarce information about the relationship of such with aerobic capacity and molecular responses involved with the performance. The overall goal of this project is based on checking the influence of the housing space of the cage as well as its interaction with the two main scientific experimental interventions (physical training or free access to activity wheel) on physiological and molecular responses related aerobic and anaerobic metabolism, body composition and stress in rats along age. In addition, to check the relationship between spontaneous and voluntary activity with physiological parameters involved with the exercise performance (AU) | |
| FAPESP's process: | 11/16222-7 - DETERMINATION OF THE SPONTANEOUS ACTIVITY OF RATS BY GRAVIMETRIC AND RELATIONS BETWEEN AEROBIC CAPACITY AND GENE EXPRESSION OF MCTS 1 AND 4: EFFECTS OF AGE AND PHYSICAL TRAINING. |
| Grantee: | Pedro Paulo Menezes Scariot |
| Support Opportunities: | Scholarships in Brazil - Master |