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Enzymatic production of N-acetyl-glucosamine by Aeromonas sp. isolated from the marine ecosystem.

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Author(s):
Flávio Augusto Cardozo
Total Authors: 1
Document type: Doctoral Thesis
Press: São Paulo.
Institution: Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB/SDI)
Defense date:
Examining board members:
Adalberto Pessoa Junior; Welington Luiz de Araujo; Ricardo Pinheiro de Souza Oliveira; Elisabete Jose Vicente; Carlota de Oliveira Rangel Yagui
Advisor: Adalberto Pessoa Junior
Abstract

N-acetyl-glucosamine (GlcNAc) is a compound of biotechnological importance with great application potential in the areas of pharmacy, medicine and dermatology. GlcNAc is currently produced by the chemical hydrolysis of chitin, the polysaccharide most abundant in the marine environment and the principal constituent of the exoskeleton of arthropods. However, the processes generally used are environmentally unfriendly, have low yield and high cost. This study demonstrates the most efficient processes for enzymatic production of N-acetyl-glucosamine from -chitin using bacterial chitinases as a sustainable alternative to the current processes and A. caviae isolates with great potential for chitinases and chitin derivatives production. (AU)

FAPESP's process: 12/16824-0 - Enzymatic production of N-acetyl-glucosamine by Aeromonas sp. isolated from marine ecosystem
Grantee:Flávio Augusto Cardozo
Support Opportunities: Scholarships in Brazil - Doctorate