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Assess nasal mucociliary transportability of male and female smokers and quality of clinical practice guidelines for chronic respiratory diseases

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Author(s):
Juliana Souza Uzeloto
Total Authors: 1
Document type: Master's Dissertation
Press: Presidente Prudente. 2016-06-23.
Institution: Universidade Estadual Paulista (Unesp). Faculdade de Ciências e Tecnologia. Presidente Prudente
Defense date:
Advisor: Ercy Mara Cipulo Ramos
Abstract

Introduction: Female smokers have increased susceptibility to various diseases in the opposite sex. But there are no studies that show if there are differences in the behavior of nasal mucociliary transport between smokers men and women. It is sure that not all smokers develop chronic respiratory diseases, however, smoking is considered a major risk factor for these diseases. Thus, it is understood that in addition to evaluating the respiratory system of smokers, research in the outcome of smokers lung health is essential, since most of the patients seen in respiratory therapy is chronic pulmonary patient. Objectives: To compare the nasal mucociliary transportability of male and female smokers taking into consideration the age, anthropometric data, smoking load, hemodynamics and lung function. In addition to systematically assess the quality of guidelines for chronic respiratory diseases relevant to the practice of physiotherapy, through the AGREE II instrument and also assess the reliability of the evaluators of the AGREE II instrument. Methods: We included in the analysis a total of 70 smokers (33 men and 37 women). All responded to an initial interview to obtain personal data and smoking load, anthropometric data were measured, vital signs and carbon monoxide in exhaled air, moreover, underwent lung function test and the saccharin transit time test (STT). For analysis of the second objective guidelines indexed in the Physiotherapy Evidence Database (PEDro) on chronic respiratory diseases were evaluated by four assessors using AGREE II (six domains and two global items). Results and Conclusions: In comparison of nasal mucociliary transportability between men and women, there was no significant difference among the analyzes, even performing stratifications of variables, so the nasal mucociliary transport of men and women smokers adult apparently healthy, is similar. Moreover, the quality of evidence-based clinical practice guidelines for chronic respiratory diseases relevant to physiotherapy could be improved, particularly with regard to applicability. The number of assessors for AGREE II could be reduced because of the good inter-rater reliability. (AU)

FAPESP's process: 14/11970-3 - Influence of gender in nasal mucociliary clearance of smokers
Grantee:Juliana Souza Uzeloto
Support Opportunities: Scholarships in Brazil - Master