Effects of aerobic exercise tranining on inflammatory and oxidative stress biomarkers of perivascular adipose tissue in obese female mice

Author(s)

Teresa Maria Da Re Silva

• Document type: Master's Dissertation
• Press: Campinas, SP.
• Institution: Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia
• Defense date: 2024-08-19

Examining board members

Maria Andréia Delbin; Ana Paula Davel; Fábio Henrique da Silva

• Advisor: Maria Andréia Delbin

Abstract

The perivascular adipose tissue (PVAT) plays an important endocrine and paracrine function and aerobic exercise directly interferes with the secretory pattern of this tissue. Pro-inflammatory factors secreted by PVAT associated with oxidative stress contribute to the development of cardiovascular complications in obesity. The mechanisms responsible for PVAT dysfunction in obesity are still not fully elucidated; in fact, studies were mainly carried in male. The present study aimed to investigate the effects of aerobic exercise training on inflammatory and oxidative stress biomarkers of PVAT in obese female mice. Female mice C57BL6/JUnib (4-5 weeks) were divided into (CEUA/UNICAMP: 5849-1/2021): sedentary (SD), trained (TR), obese sedentary (OB/SD), and obese trained (OB/TR)... Abstract is available with the full the electronic document (AU)

• FAPESP's process: 22/10354-3 - Effects of aerobic exercise training on inflammatory, oxidative stress and senescence biomarkers of perivascular adipose tissue in obese female mice
• Grantee: Teresa Maria da Ré Silva
• Support Opportunities: Scholarships in Brazil - Master