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Impact of obsessive compulsive disorder treatment on psychiatric comorbidities in the short and in the mean follow-up

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Author(s):
Carolina Valerio
Total Authors: 1
Document type: Master's Dissertation
Press: São Paulo.
Institution: Universidade de São Paulo (USP). Faculdade de Medicina (FM/SBD)
Defense date:
Examining board members:
Roseli Gedanke Shavitt; Maria Conceição do Rosário Campos; Katia Cristina Lima de Petribu
Advisor: Roseli Gedanke Shavitt
Abstract

Obsessive-compulsive disorder (OCD) is an anxiety disorder characterized by the presence of obsessions and/or compulsions that cause great impairment in the daily life of patients. Obsessions are thoughts, images, ideas or impulses that are persistent and experienced as intrusive, repetitive and cause anxiety or distress. Compulsions are repetitive behaviors or mental acts executed, in general, in response to obsessions and are intended to prevent or reduce the distress caused by them. OCD is also a chronic disorder that present high rates of psychiatric comorbidities such as depression, tic disorders and other anxiety disorders, and there is some evidence that the higher the number of psychiatric comorbidities, the worse the OCD treatment response. However, little is known about the impact of OCD treatment on the outcome of the psychiatric comorbidities usually present in OCD patients. The aim of this study was to investigate the impact of exclusive, conventional treatments for OCD on the outcome of additional psychiatric disorders of OCD patients detected at baseline. Patients with primary OCD admitted to the treatment protocols of the Obsessive-Compulsive Spectrum Disorders Program (PROTOC - IPq-HC-FMUSP), between July 2007 and December 2009, were evaluated at pre-treatment and after 3 and 12 months, with regard to OCD treatment response and psychiatric comorbidities status. The data were analyzed to verify possible associations between OCD treatment response and the outcome of psychiatric comorbidities. Results showed a significant association between OCD treatment response and improvement of major depression, dysthimia, other anxiety and tic disorders. Further research focusing on the possible mechanisms by which OCD treatment could lead to improvement of these specific disorders is warranted. (AU)

FAPESP's process: 08/55855-2 - Impact of obsessive compulsive disorder treatment on psychiatric comorbidities in the short and in the mean follow-up
Grantee:Carolina Valerio
Support Opportunities: Scholarships in Brazil - Master